Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | BPTF | Q12830 | 1/20 | 0.36 |
| ▸ | PDE9A | O76083 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
| ▸ | BCHE | P06276 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9726472 | 0.92 | NPC1 (0.43) | NPC1RAB9AMEN1KMT2ABPTF | |
| SCHEMBL9726512 | 0.72 | BRD4 (0.47) | NPC1RAB9AMEN1KMT2ABPTF | |
| SCHEMBL9726707 | 0.72 | BRD4 (0.45) | RAB9ABPTFPDE9AALDH1A1 | |
| SCHEMBL9726500 | 0.69 | BRD4 (0.46) | BPTFPDE9AALDH1A1 | |
| SCHEMBL9726526 | 0.68 | BRD4 (0.44) | BPTFPDE9AALDH1A1 | |
| SCHEMBL9726528 | 0.67 | BRD4 (0.52) | BPTFPDE9AKDM4EALDH1A1GAA | |
| SCHEMBL9726408 | 0.66 | BRD4 (0.42) | RAB9AMEN1KMT2ABPTFPDE9A | |
| SCHEMBL9726508 | 0.65 | BRD4 (0.52) | RAB9AMEN1KMT2ABPTFPDE9A | |
| SCHEMBL10367542 | 0.61 | BPTF (0.42) | RAB9ABPTFALDH1A1GAA | |
| SCHEMBL31361968 | 0.61 | ALDH1A1 (0.52) | KDM4EALDH1A1GAACYP2D6GGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098900-A | Reducing contractions in smooth muscles | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-03-24 | — | — | US | disclosed |
| EP-0186817-B1 | 3(2H)PYRIDAZINONE, PROCESS FOR ITS PREPARATION AND ANTI-ALLERGIC AGENT CONTAINING IT | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1989-08-02 | — | — | EP | disclosed |