Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 2/20 | 0.49 |
| ▸ | KAT2B | Q92831 | 4/20 | 0.43 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BRD2 | P25440 | 1/20 | 0.33 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PDE9A | O76083 | 3/20 | 0.32 |
| ▸ | PDE1A | P54750 | 1/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9234085 | 0.81 | BPTF (0.48) | BPTFKAT2BBRD4BRD2BRD3 | |
| SCHEMBL10366081 | 0.78 | BPTF (0.46) | BPTFKAT2BPDE1CBRD4BRD2 | |
| SCHEMBL9930351 | 0.76 | BPTF (0.34) | BPTFCYP1A2CYP2C19DRD4 | |
| SCHEMBL7010722 | 0.75 | KAT2B (0.56) | BPTFKAT2BBRD4BRD9GAA | |
| SCHEMBL9726422 | 0.72 | BPTF (0.40) | BPTFKAT2BPDE1CBRD4BRD2 | |
| SCHEMBL144678 | 0.71 | PIK3CD (0.30) | — | |
| SCHEMBL11272569 | 0.70 | SMN1; SMN2 (0.46) | BPTFKAT2BPDE1CBRD9KMT2A | |
| SCHEMBL5021281 | 0.70 | CYP1A2 (0.33) | CYP1A2DRD4 | |
| SCHEMBL10366093 | 0.69 | BPTF (0.42) | BPTFKAT2BPDE1CBRD4BRD2 | |
| SCHEMBL10367542 | 0.69 | BPTF (0.42) | BPTFKAT2BPDE1CGAAPDE1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098900-A | Reducing contractions in smooth muscles | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-03-24 | — | — | US | disclosed |
| EP-0186817-B1 | 3(2H)PYRIDAZINONE, PROCESS FOR ITS PREPARATION AND ANTI-ALLERGIC AGENT CONTAINING IT | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1989-08-02 | — | — | EP | disclosed |
| EP-0186817-A1 | 3(2H)pyridazinone, process for its preparation and anti-allergic agent containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1986-07-09 | — | — | EP | disclosed |