SCHEMBL144678

SCHEMBL144678

CC(C)n1ncc(N)c1N

nearest known ligand 0.30

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.30
ABL1 P00519 1/20 0.30
EGFR P00533 1/20 0.30
HCK P08631 1/20 0.30
SRC P12931 1/20 0.30
KDR P35968 1/20 0.30
PIK3CA P42336 1/20 0.30
PIK3CB P42338 1/20 0.30
MTOR P42345 1/20 0.30
PIK3CG P48736 1/20 0.30
EPHB4 P54760 1/20 0.30
PRKDC P78527 1/20 0.30
PI4KB Q9UBF8 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL2921878 0.88 FPR1 (0.32) KDM4E
SCHEMBL4730392 0.84
SCHEMBL94060 0.82
SCHEMBL14321038 0.82
SCHEMBL23234657 0.82 KDM4E (0.32) KDM4E
SCHEMBL5160602 0.80
SCHEMBL691173 0.79 TSHR (0.39)
SCHEMBL5021281 0.79 CYP1A2 (0.33)
SCHEMBL1497962 0.79
SCHEMBL5393771 0.79 L3MBTL1 (0.34) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1343 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12383482-B2 Hair coloring compositions WELLA GERMANY GMBH (DE) 2025-08-12 US claimed
EP-4251285-B1 HAIR COLORING COMPOSITIONS WELLA INT OPERATIONS SWITZERLAND SARL (CH) 2024-09-04 EP claimed
US-20240024218-A1 HAIR COLORING COMPOSITIONS WELLA GERMANY GMBH (DE) 2024-01-25 US claimed
CN-117396185-A Hair dyeing composition 威娜国际运营瑞士责任有限公司 2024-01-12 CN claimed
US-11142498-B2 Keratin dyeing compounds, compositions containing them, and method and use thereof WELLA OPERATIONS US, LLC (US) 2021-10-12 US claimed
US-20200247749-A1 KERATIN DYEING COMPOUNDS, COMPOSITIONS CONTAINING THEM, AND METHOD AND USE THEREOF WELLA OPERATIONS US, LLC 2020-08-06 US claimed
US-10639257-B2 Composition for colouring keratin fibres BEAUTY & BUSINESS S.P.A. (IT) 2020-05-05 US claimed
EP-3263180-B1 METHOD FOR COLORING HAIR FIBERS INTO A FIRST AND A SECOND PATTERNS NOXELL CORP (US) 2020-04-08 EP claimed
US-20190269945-A1 METHOD FOR COLORING HAIR FIBERS INTO A FIRST AND A SECOND PATTERNS NOXELL CORP (US) 2019-09-05 US claimed
EP-3281623-B1 HAIR COLORING COMPOSITION FOR PROVIDING A FILM ON KERATIN FIBERS NOXELL CORP (US) 2019-07-31 EP claimed
EP-1166748-A2 Agent and process for colouring keratinic fibres Wella Aktiengesellschaft (DE) 2002-01-02 EP claimed
EP-1166749-A2 Composition and process for dyeing keratinic fibres Wella Aktiengesellschaft (DE) 2002-01-02 EP claimed
EP-1158954-A1 MEANS AND METHOD FOR DYING KERATINIC FIBRES Wella Aktiengesellschaft (DE) 2001-12-05 EP claimed
WO-2001070182-A1 AGENT AND METHOD FOR COLOURING KERATIN FIBRES WELLA AKTIENGESELLSCHAFT (DE) 2001-09-27 WO claimed
US-20010009044-A1 Oxidative hair dye precursor compositions containing 4-5-diaminopyrazole, 5-amino-2-methylphenol and m-phenylenediamine compounds and method of dyeing hair HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) 2001-07-26 US claimed
WO-2001051019-A1 MEANS AND METHOD FOR DYING KERATINIC FIBRES WELLA AKTIENGESELLSCHAFT (DE) 2001-07-19 WO claimed
WO-2001034104-A1 COLOURING AGENT FOR KERATIN CONTAINING FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-05-17 WO claimed
US-5645610-A COUPLER, DEVELOPER WELLA AKTIENGESELLSCHAFT (DE) 1997-07-08 US claimed
US-5637115-A Oxidation hair dye compositions containing developers, couplers, and AZO dyes WELLA AKTIENGESELLSCHAT (DE) 1997-06-10 US claimed
EP-0687669-A1 Hair dyeing compositions and new 2-alkylamino-4-amino-1-alkylbenzenes Wella Aktiengesellschaft (DE) 1995-12-20 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11142498-B2 Keratin dyeing compounds, compositions containing them, and method and use thereof KRT18, MARK4, MKI67 PIK3CD 1984/4885ABL1 2338/4885EGFR 3217/4885
US-20190269945-A1 METHOD FOR COLORING HAIR FIBERS INTO A FIRST AND A SECOND PATTERNS COXFA4L2, KRT18, SHH PIK3CD 4543/4885ABL1 4782/4885EGFR 4658/4885
US-20200247749-A1 KERATIN DYEING COMPOUNDS, COMPOSITIONS CONTAINING THEM, AND METHOD AND USE THEREOF KRT18, PRKDC, MKI67 PIK3CD 1862/4885ABL1 2327/4885EGFR 3153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.