Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 2/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDE1A | P54750 | 1/20 | 0.35 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | BRD2 | P25440 | 2/20 | 0.33 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9234085 | 0.82 | BPTF (0.48) | BPTFKAT2BALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL29451464 | 0.81 | ALDH1A1 (0.46) | ALDH1A1HTTSMN1; SMN2RAB9ALMNA | |
| SCHEMBL12411024 | 0.80 | BPTF (0.36) | BPTFKAT2BALDH1A1SMN1; SMN2PDE1C | |
| SCHEMBL29451818 | 0.76 | MAPT (0.44) | ALDH1A1HTTSMN1; SMN2RAB9AMAPT | |
| SCHEMBL4360057 | 0.75 | CYP1A2 (0.35) | BPTFKAT2BPDE1CPDE9A | |
| SCHEMBL8544499 | 0.74 | BRD9 (0.48) | BPTFKAT2BALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL22041006 | 0.73 | CYP1A2 (0.39) | BPTFKAT2BALDH1A1PDE1CPDE1A | |
| SCHEMBL4347184 | 0.73 | DRD4 (0.35) | BPTFKAT2BPDE1CPDE9A | |
| SCHEMBL9726491 | 0.72 | BPTF (0.49) | BPTFKAT2BALDH1A1SMN1; SMN2PDE1C | |
| SCHEMBL10366081 | 0.72 | BPTF (0.46) | BPTFKAT2BALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098900-A | Reducing contractions in smooth muscles | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-03-24 | — | — | US | disclosed |
| EP-0186817-B1 | 3(2H)PYRIDAZINONE, PROCESS FOR ITS PREPARATION AND ANTI-ALLERGIC AGENT CONTAINING IT | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1989-08-02 | — | — | EP | disclosed |
| EP-0186817-A1 | 3(2H)pyridazinone, process for its preparation and anti-allergic agent containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1986-07-09 | — | — | EP | disclosed |