Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 6/20 | 0.54 |
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.54 |
| ▸ | BPTF | Q12830 | 2/20 | 0.53 |
| ▸ | KAT2B | Q92831 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PDE9A | O76083 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9726627 | 0.92 | BRD4 (0.52) | BRD4BRD9BPTFKAT2BMAPT | |
| SCHEMBL9726399 | 0.88 | BRD4 (0.49) | BRD4BRD9BPTFKAT2BMAPT | |
| SCHEMBL9726483 | 0.87 | BRD4 (0.41) | BRD4BRD9BPTFKAT2BMAPT | |
| SCHEMBL9726528 | 0.85 | BRD4 (0.52) | BRD4BRD9BPTFKAT2BMAPT | |
| SCHEMBL10601520 | 0.84 | BRD4 (0.74) | BRD4BRD9BPTFKAT2BMAPT | |
| SCHEMBL9726487 | 0.83 | BRD4 (0.50) | BRD4BRD9BPTFKAT2BMAPT | |
| SCHEMBL9726575 | 0.80 | BRD4 (0.47) | BRD4BRD9BPTFKAT2BGRM2 | |
| SCHEMBL9726489 | 0.79 | ALDH1A1 (0.46) | BRD4BRD9BPTFKAT2BMAPT | |
| SCHEMBL9726443 | 0.79 | BACE1 (0.43) | BRD4BRD9BPTFALDH1A1GRM2 | |
| SCHEMBL9726619 | 0.76 | BRD4 (0.49) | BRD4BRD9BPTFKAT2BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098900-A | Reducing contractions in smooth muscles | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-03-24 | — | — | US | claimed |
| EP-0186817-B1 | 3(2H)PYRIDAZINONE, PROCESS FOR ITS PREPARATION AND ANTI-ALLERGIC AGENT CONTAINING IT | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1989-08-02 | — | — | EP | claimed |
| EP-0186817-A1 | 3(2H)pyridazinone, process for its preparation and anti-allergic agent containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1986-07-09 | — | — | EP | claimed |