Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 5/20 | 0.48 |
| ▸ | BPTF | Q12830 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.46 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.45 |
| ▸ | JAK3 | P52333 | 1/20 | 0.45 |
| ▸ | PDE5A | O76074 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9726448 | 0.92 | BRD4 (0.47) | BRD4BPTFALDH1A1HPGDALOX15 | |
| SCHEMBL9726674 | 0.87 | BRD4 (0.44) | BRD4BPTFALDH1A1HPGDALOX15 | |
| SCHEMBL9726619 | 0.86 | BRD4 (0.49) | BRD4BPTFALDH1A1KDM4EPOLB | |
| SCHEMBL9726673 | 0.85 | BRD4 (0.46) | BRD4BPTFALDH1A1KDM4EPOLB | |
| SCHEMBL9726613 | 0.84 | BPTF (0.49) | BRD4BPTFALDH1A1HPGDALOX15 | |
| SCHEMBL9726487 | 0.83 | BRD4 (0.50) | BRD4BPTFALDH1A1KDM4EPOLB | |
| SCHEMBL9726415 | 0.82 | BRD4 (0.49) | BRD4BPTFALDH1A1HPGDKDM4E | |
| SCHEMBL9828337 | 0.81 | BRD4 (0.46) | BRD4BPTFALDH1A1HPGDKDM4E | |
| SCHEMBL9726489 | 0.78 | ALDH1A1 (0.46) | BRD4BPTFALDH1A1KDM4EPOLB | |
| SCHEMBL9726824 | 0.77 | PDE9A (0.49) | BRD4BPTFALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098900-A | Reducing contractions in smooth muscles | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-03-24 | — | — | US | disclosed |
| EP-0186817-B1 | 3(2H)PYRIDAZINONE, PROCESS FOR ITS PREPARATION AND ANTI-ALLERGIC AGENT CONTAINING IT | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1989-08-02 | — | — | EP | disclosed |
| EP-0186817-A1 | 3(2H)pyridazinone, process for its preparation and anti-allergic agent containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1986-07-09 | — | — | EP | disclosed |