SCHEMBL9726709

SCHEMBL9726709

CCCN(CCC)CCNC=O

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ADH1B P00325 4/20 0.56
ADH1A P07327 4/20 0.56
ADH7 P40394 3/20 0.56
ADH1C P00326 3/20 0.52
EPHX1 P07099 1/20 0.50
ADH4 P08319 1/20 0.50
ALDH1A1 P00352 2/20 0.32
DRD2 P14416 1/20 0.32
DRD4 P21917 1/20 0.32
DRD3 P35462 1/20 0.32
TSHR P16473 1/20 0.31
CA12 O43570 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16995353 0.87 ADH1B (0.43) ADH1BADH1AADH7ADH1CEPHX1
SCHEMBL12894209 0.86 ADH1B (0.60) ADH1BADH1AADH7ADH1CEPHX1
SCHEMBL5257037 0.86 ADH1B (0.60) ADH1BADH1AADH7ADH1CEPHX1
SCHEMBL21096355 0.85 ADH1B (0.42) ADH1BADH1AADH7ADH1CEPHX1
SCHEMBL93173 0.83 ADH1B (0.52) ADH1BADH1AADH7ADH1CEPHX1
SCHEMBL16995385 0.82 ADH1B (0.43) ADH1BADH1AADH7ADH1CEPHX1
SCHEMBL19622850 0.82 ADH1B (0.43) ADH1BADH1AADH7ADH1CEPHX1
SCHEMBL27269307 0.81 ADH1A (0.63) ADH1BADH1AADH7ADH1CEPHX1
SCHEMBL29037600 0.81 ADH1A (0.63) ADH1BADH1AADH7ADH1CEPHX1
Hydrochloric Acid SCHEMBL4811854 0.81 ADH1B (0.50) ADH1BADH1AADH7ADH1CEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5098900-A Reducing contractions in smooth muscles NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1992-03-24 US disclosed
EP-0186817-B1 3(2H)PYRIDAZINONE, PROCESS FOR ITS PREPARATION AND ANTI-ALLERGIC AGENT CONTAINING IT NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1989-08-02 EP disclosed
EP-0186817-A1 3(2H)pyridazinone, process for its preparation and anti-allergic agent containing it NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1986-07-09 EP disclosed