Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.43 |
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | BPTF | Q12830 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.36 |
| ▸ | GPR183 | P32249 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9726805 | 0.82 | BRD4 (0.53) | BRD4BRD9KAT2BSMN1; SMN2MEN1 | |
| SCHEMBL10871305 | 0.81 | BRD4 (0.42) | BRD4BRD9KAT2BSMN1; SMN2MEN1 | |
| SCHEMBL9726479 | 0.78 | BRD4 (0.50) | BRD4BRD9KAT2BSMN1; SMN2MEN1 | |
| SCHEMBL9726461 | 0.78 | BRD4 (0.49) | BRD4BRD9KAT2BSMN1; SMN2MEN1 | |
| SCHEMBL9726537 | 0.77 | BRD4 (0.45) | BRD4BRD9KAT2BSMN1; SMN2MEN1 | |
| SCHEMBL9726412 | 0.73 | BRD4 (0.53) | BRD4BRD9KAT2BSMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL9726406 | 0.72 | BRD4 (0.52) | BRD4BRD9KAT2BSMN1; SMN2MEN1 | |
| SCHEMBL21442514 | 0.69 | BRD4 (0.47) | BRD4BRD9KAT2BSMN1; SMN2MEN1 | |
| SCHEMBL9726566 | 0.68 | LMNA (0.47) | BRD4BRD9KAT2BSMN1; SMN2MEN1 | |
| SCHEMBL17074608 | 0.67 | CNR2 (0.56) | BRD4BRD9KAT2BSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5098900-A | Reducing contractions in smooth muscles | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-03-24 | — | — | US | disclosed |
| EP-0186817-B1 | 3(2H)PYRIDAZINONE, PROCESS FOR ITS PREPARATION AND ANTI-ALLERGIC AGENT CONTAINING IT | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1989-08-02 | — | — | EP | disclosed |
| EP-0186817-A1 | 3(2H)pyridazinone, process for its preparation and anti-allergic agent containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1986-07-09 | — | — | EP | disclosed |