Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.45 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9726979 | 0.85 | KMT2A (1.00) | KMT2AMEN1HCRTR1HCRTR2DDB1 | |
| SCHEMBL26617203 | 0.81 | KMT2A (0.47) | KMT2AMEN1GRIN1GRIN2ASMN1; SMN2 | |
| SCHEMBL1951070 | 0.78 | KMT2A (0.64) | KMT2AMEN1HCRTR1HCRTR2DDB1 | |
| SCHEMBL5093540 | 0.75 | KMT2A (0.73) | KMT2AMEN1HCRTR1HCRTR2DDB1 | |
| SCHEMBL12641233 | 0.75 | MEN1 (0.64) | KMT2AMEN1HCRTR1HCRTR2DDB1 | |
| SCHEMBL26617223 | 0.75 | KMT2A (0.76) | KMT2AMEN1HCRTR1HCRTR2DDB1 | |
| SCHEMBL4619569 | 0.75 | SMN1; SMN2 (0.71) | KMT2AMEN1DDB1CRBNL3MBTL1 | |
| SCHEMBL9726950 | 0.73 | GRIN1 (0.43) | KMT2AMEN1GRIN1GRIN2ACYP2D6 | |
| SCHEMBL14016406 | 0.72 | KMT2A (0.56) | KMT2AMEN1HCRTR1HCRTR2DDB1 | |
| SCHEMBL17608847 | 0.72 | LTA4H (0.62) | KMT2AMEN1CXCR3CYP2D6OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128466-A | For monitoring lithium levels in patients receiving lithium treatment for depression | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1992-07-07 | — | — | US | disclosed |