Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 6/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 7/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727040 | 0.85 | MEN1 (0.49) | USP2CYP3A4CYP2D6CYP1A2TP53 | |
| SCHEMBL19341589 | 0.75 | USP2 (0.51) | USP2CYP3A4CYP2D6CYP1A2TP53 | |
| SCHEMBL9726828 | 0.73 | KMT2A (0.74) | GRIN1GRIN2ACYP2D6OPRM1OPRD1 | |
| SCHEMBL19341586 | 0.72 | OPRM1 (0.53) | GRIN1GRIN2AUSP2CYP3A4CYP2D6 | |
| SCHEMBL5563143 | 0.68 | KMT2A (0.48) | USP2CYP3A4CYP2D6CYP1A2OPRM1 | |
| SCHEMBL19347109 | 0.68 | CYP3A4 (0.56) | USP2CYP3A4CYP2D6CYP1A2TP53 | |
| SCHEMBL9726922 | 0.66 | GRIN1 (0.38) | GRIN1GRIN2AGRIN2B | |
| SCHEMBL7043309 | 0.65 | GRIN1 (0.42) | GRIN1GRIN2AUSP2CYP3A4CYP2D6 | |
| SCHEMBL7043301 | 0.65 | GRIN1 (0.41) | GRIN1GRIN2AUSP2CYP3A4CYP2D6 | |
| SCHEMBL6730231 | 0.63 | GRIN1 (0.40) | GRIN1GRIN2AOPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128466-A | For monitoring lithium levels in patients receiving lithium treatment for depression | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1992-07-07 | — | — | US | disclosed |