Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1813861 | 0.63 | ALDH1A1 (0.49) | ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL635693 | 0.61 | ALDH1A1 (0.48) | ALDH1A1MEN1MAPTKMT2A | |
| Nitric Acid SCHEMBL9726892 | 0.59 | CA5A (0.31) | — | |
| SCHEMBL3192408 | 0.57 | ALDH1A1 (0.51) | ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL131785 | 0.51 | MEN1 (0.38) | MEN1KMT2A | |
| SCHEMBL16178868 | 0.50 | — | — | |
| SCHEMBL31678563 | 0.45 | MEN1 (0.75) | ALDH1A1MEN1KMT2A | |
| SCHEMBL651428 | 0.45 | MEN1 (0.75) | ALDH1A1MEN1KMT2A | |
| SCHEMBL4365635 | 0.44 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL8967528 | 0.44 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1032648-C | Process for preparation of platelet activating factor antagonist | FIZER LTD (GB) | 1996-08-28 | — | — | CN | disclosed |
| US-5149814-A | Alkyl 2-benzylidene-4-(2-alkylimidazopyrid-1-yl) benzoylacetate esters as intermediate compounds | PFIZER INC (US) | 1992-09-22 | — | — | US | disclosed |
| US-5120747-A | Antiallergens, antiinflammatory agent | PFIZER INC. (US) | 1992-06-09 | — | — | US | disclosed |
| US-5070205-A | Chemical intermediate for anticoagulants | PFIZER INC. (US) | 1991-12-03 | — | — | US | disclosed |
| EP-0310386-B1 | 4-ARYL-5-CARBAMOYL-1,4-DIHYDROPYRIDINES | Pfizer Limited (GB) | 1991-11-06 | — | — | EP | disclosed |
| US-5063237-A | Antiallergens and antiinflammatory agents | PFIZER INC. (US) | 1991-11-05 | — | — | US | disclosed |
| US-4935430-A | Platelet activating factor antagonists | PFIZER INC. (US) | 1990-06-19 | — | — | US | disclosed |
| CN-1032439-A | A kind of preparation method of platelet-activating factor antagonist | PFIZER LTD (GB) | 1989-04-19 | — | — | CN | disclosed |
| EP-0310386-A2 | 4-Aryl-5-carbamoyl-1,4-dihydropyridines | Pfizer Limited (GB) | 1989-04-05 | — | — | EP | disclosed |