Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17629453 | 0.64 | CES1 (0.36) | ALDH1A1 | |
| SCHEMBL9623158 | 0.63 | TDP1 (0.51) | ALDH1A1 | |
| SCHEMBL3660300 | 0.63 | — | — | |
| SCHEMBL13770918 | 0.62 | ALDH1A1 (0.45) | PTPN1ALDH1A1 | |
| SCHEMBL3628864 | 0.60 | — | — | |
| SCHEMBL6444424 | 0.55 | — | — | |
| SCHEMBL4448067 | 0.55 | — | — | |
| SCHEMBL6434544 | 0.55 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL18726373 | 0.54 | HSP90AA1 (0.31) | — | |
| SCHEMBL14591132 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8524896-B2 | Chemical compounds | SYNGENTA CROP PROTECTION LLC (US) | 2013-09-03 | — | — | US | disclosed |
| EP-2500340-A1 | 2-Cyanophenyl Sulfonamide Derivatives Useful as Pesticides | Syngenta Participations AG. (CH) | 2012-09-19 | — | — | EP | disclosed |
| US-20110009261-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-01-13 | — | — | US | disclosed |
| EP-2265579-A2 | 2-CYANOBENZENSULFONAMIDE DERIVATIVES HAVING PESTICIDAL PROPERTIES | Syngenta Participations AG (CH) | 2010-12-29 | — | — | EP | disclosed |
| US-20100311582-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-12-09 | — | — | US | disclosed |
| EP-2231632-A2 | 2-CYANOPHENYL SULFONAMIDE DERIVATIVES USEFUL AS PESTICIDES | Syngenta Participations AG (CH) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009109539-A2 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-09-11 | — | — | WO | disclosed |
| WO-2009092590-A2 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-07-30 | — | — | WO | disclosed |
| WO-2009087085-A2 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-07-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009261-A1 | CHEMICAL COMPOUNDS | CBR3, CBR1, CYCS | PTPN1 1980/4885ALDH1A1 3381/4885 |
| US-20100311582-A1 | CHEMICAL COMPOUNDS | CBR3, CBR1, CCNY | PTPN1 914/4885ALDH1A1 3581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.