Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.54 |
| ▸ | HMGCR | P04035 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 3/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.53 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | TYR | P14679 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | BLM | P54132 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5610217 | 0.86 | HTT (0.52) | HTTNR1I2HMGCRCA2CA1 | |
| SCHEMBL27564554 | 0.83 | HTT (0.53) | HTTNR1I2HMGCRCA2CA1 | |
| SCHEMBL2189364 | 0.83 | HTT (0.49) | HTTNR1I2HMGCRCA2CA1 | |
| SCHEMBL8072537 | 0.82 | GABBR2 (0.58) | HTTNR1I2HMGCRCA2CA1 | |
| SCHEMBL8072535 | 0.82 | GABBR2 (0.58) | HTTNR1I2HMGCRCA2CA1 | |
| SCHEMBL85764 | 0.80 | GABBR2 (0.66) | HTTHMGCRCA2CA1GABBR2 | |
| SCHEMBL6071609 | 0.80 | HTT (0.46) | HTTNR1I2HMGCRCA2CA1 | |
| SCHEMBL15299843 | 0.80 | HTT (0.46) | HTTNR1I2HMGCRCA2CA1 | |
| SCHEMBL14472045 | 0.79 | HTT (0.63) | HTTCA2CA1GABBR2GABBR1 | |
| SCHEMBL1821480 | 0.79 | PTGS1 (0.74) | HTTCA2CA1GABBR2GABBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169925-A | Light stabilizers for polymers; photooxidation resistance; nondestructive; nondiffusing; heat resistance; molding materials | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-12-08 | — | — | US | disclosed |
| US-4198334-A | HEAT, LIGHT, OXIDATION RESISTANCE, PLASTICS | CIBA-GEIGY CORPORATION (US) | 1980-04-15 | — | — | US | disclosed |