SCHEMBL2189364

SCHEMBL2189364

CCCC[CH]c1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.49
GABBR2 O75899 2/20 0.46
GABBR1 Q9UBS5 2/20 0.46
CA2 P00918 2/20 0.45
CA1 P00915 1/20 0.45
ALDH1A1 P00352 4/20 0.45
CYP1A2 P05177 4/20 0.45
PTGS1 P23219 3/20 0.45
PTGS2 P35354 3/20 0.45
CYP2C9 P11712 3/20 0.45
CYP3A4 P08684 3/20 0.45
TSHR P16473 3/20 0.45
MAPT P10636 3/20 0.45
LMNA P02545 3/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
MEN1 O00255 2/20 0.45
BLM P54132 2/20 0.45
KMT2A Q03164 2/20 0.45
HIF1A Q16665 2/20 0.45
NPSR1 Q6W5P4 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15299843 0.93 HTT (0.46) HTTGABBR2GABBR1CA2CA1
SCHEMBL6071609 0.93 HTT (0.46) HTTGABBR2GABBR1CA2CA1
SCHEMBL5610217 0.89 HTT (0.52) HTTGABBR2GABBR1CA2CA1
SCHEMBL9727016 0.83 HTT (0.57) HTTGABBR2GABBR1CA2CA1
SCHEMBL4410555 0.79 HTT (0.42) HTTGABBR2GABBR1CA2CA1
SCHEMBL4565952 0.78 GABBR2 (0.50) HTTGABBR2GABBR1ALDH1A1CYP1A2
SCHEMBL4565953 0.78 GABBR2 (0.50) HTTGABBR2GABBR1ALDH1A1CYP1A2
SCHEMBL11867839 0.76 GABBR2 (0.47) HTTGABBR2GABBR1CA2CA1
SCHEMBL27564554 0.76 HTT (0.53) HTTGABBR2GABBR1CA2CA1
Butylated Hydroxytoluene SCHEMBL28288111 0.73 CA2 (0.75) GABBR2GABBR1CA2CA1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1885787-B1 PHOSPHITE ADDITIVES IN POLYOLEFINS PHILLIPS PETROLEUM CO (US) 2018-01-10 EP claimed
EP-4150001-A1 POLYETHYLENE HOMOPOLYMER COMPOSITIONS WITH BALANCED PROPERTIES Nova Chemicals (International) S.A. (CH) 2023-03-22 EP disclosed
WO-2021229354-A1 POLYETHYLENE HOMOPOLYMER COMPOSITIONS WITH BALANCED PROPERTIES NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) 2021-11-18 WO disclosed
CN-101495591-B Silane functional adhesive composition and method of bonding a window to a substrate without a primer DOW GLOBAL TECHNOLOGIES INC 2011-11-16 CN disclosed
EP-2342766-A1 POWER LED DEVICE WITH A REFLECTOR MADE OF AROMATIC POLYESTER AND/OR WHOLLY AROMATIC POLYESTER Solvay Advanced Polymers, L.L.C. (US) 2011-07-13 EP disclosed
WO-2010049531-A1 POWER LED DEVICE WITH A REFLECTOR MADE OF AROMATIC POLYESTER AND/OR WHOLLY AROMATIC POLYESTER SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2010-05-06 WO disclosed
CN-101495591-A Silane functional adhesive composition and method of bonding a window to a substrate without a primer DOW GLOBAL TECHNOLOGIES INC (US) 2009-07-29 CN disclosed
EP-1498442-B1 Method for the preparation of a polyester block copolymer composition DAICEL CHEM (JP) 2009-02-11 EP disclosed
US-7196123-B2 Polyester block copolymer composition and process for the preparation thereof WATANABE JUN 2007-03-27 US disclosed
EP-1498442-A2 Method for the preparation of a polyester block copolymer, a polyester block copolymer composition and method for the preparation thereof Daicel Chemical Industries, Ltd. (JP) 2005-01-19 EP disclosed
EP-1151034-A1 PHOSPHITE ADDITIVES IN POLYOLEFINS Phillips Petroleum Company (US) 2001-11-07 EP disclosed
EP-1120432-A1 PROCESS FOR THE PRODUCTION OF POLYESTER BLOCK COPOLYMERS, POLYESTER BLOCK COPOLYMER COMPOSITIONS AND PROCESS FOR THE PREPARATION THEREOF DAICEL CHEMICAL INDUSTRIES, Ltd. (JP) 2001-08-01 EP disclosed
WO-2000023514-A1 PHOSPHITE ADDITIVES IN POLYOLEFINS PHILLIPS PETROLEUM COMPANY (US) 2000-04-27 WO disclosed
EP-0613891-B1 2-(Benzotriazol-2-yl)-4-alkyl-6-(2-hydroxy-3-benzoylbenzyl)phenols and stabilized compositions CIBA GEIGY AG (CH) 1996-08-28 EP disclosed
EP-0682680-A1 ELECTRO COAT/BASE COAT/CLEAR COAT FINISHES STABILIZED WITH s-TRIAZINE UV ABSORBERS Ciba SC Holding AG (CH) 1995-11-22 EP disclosed
EP-0613891-A1 2-(Benzotriazol-2-yl)-4-alkyl-6-(2-hydroxy-3-benzoylbenzyl)phenols and stabilized compositions CIBA-GEIGY AG (CH) 1994-09-07 EP disclosed
WO-1994018278-A2 ELECTRO COAT/BASE COAT/CLEAR COAT FINISHES STABILIZED WITH s-TRIAZINE UV ABSORBERS CIBA-GEIGY AG (CH) 1994-08-18 WO disclosed
EP-0514333-A2 Substituted 1,4-diamino-2-butene stabilizers and stabilized compositions CIBA-GEIGY AG (CH) 1992-11-19 EP disclosed
EP-0483060-A2 Sterically hindered oxime color improvers for polyolefin processing CIBA-GEIGY AG (CH) 1992-04-29 EP disclosed
EP-0226538-A2 Light stabilized polymer microparticles CIBA-GEIGY AG (CH) 1987-06-24 EP disclosed