Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | HSD11B1 | P28845 | 7/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.45 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7383735 | 0.82 | MMP2 (0.64) | TP53LMNAGAAHSD11B1ALDH1A1 | |
| SCHEMBL7379601 | 0.79 | MMP2 (0.64) | TP53LMNAGAAACHE | |
| SCHEMBL10702282 | 0.79 | MMP2 (0.64) | TP53GAAPOLB | |
| SCHEMBL7380549 | 0.78 | PKM (0.62) | TP53LMNAGAAALDH1A1 | |
| SCHEMBL9727536 | 0.78 | TSHR (0.59) | TP53GAA | |
| SCHEMBL9727624 | 0.78 | GAA (0.48) | TP53GAAALDH1A1 | |
| SCHEMBL25348950 | 0.78 | MMP2 (0.62) | TP53LMNAGAAALDH1A1POLB | |
| SCHEMBL9727326 | 0.77 | GAA (0.47) | TP53GAA | |
| SCHEMBL7094393 | 0.76 | MMP2 (0.60) | TP53GAAALDH1A1POLB | |
| SCHEMBL9727635 | 0.76 | GAA (0.46) | TP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5164514-A | Antispasmodics | ROUSSEL UCLAF (FR) | 1992-11-17 | — | — | US | claimed |
| US-4990531-A | Antispasmodic agents | ROUSSEL UCLAF (FR) | 1991-02-05 | — | — | US | claimed |
| EP-0335758-A2 | Derivatives of 1-arylsulfonyl-2-pyrolidinone, process for their preparation, their use as medicaments and compositions containing them | ROUSSEL-UCLAF (FR) | 1989-10-04 | — | — | EP | claimed |
| JP-1287070-A | — | — | None | — | — | JP | disclosed |
| US-5164514-A | Antispasmodics | ROUSSEL UCLAF (FR) | 1992-11-17 | — | — | US | disclosed |
| US-5081130-A | Antispasmodic agents | ROUSSEL UCLAF (FR) | 1992-01-14 | — | — | US | disclosed |
| US-4990531-A | Antispasmodic agents | ROUSSEL UCLAF (FR) | 1991-02-05 | — | — | US | disclosed |
| JP-H01287070-A | NEW 1-ARYLSULFONYL2-PYRROLIDINONE DERIVATIVES, THEIR PRODUCTION, NEW INTERMEDIATES OBTAINED, THEIR USE AS MEDICINES AND COMPOSITION CONTAINING THEM | ROUSSEL UCLAF | 1989-11-17 | — | — | JP | disclosed |