Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 3/20 | 0.55 |
| ▸ | NMUR2 | Q9GZQ4 | 8/20 | 0.55 |
| ▸ | NMUR1 | Q9HB89 | 8/20 | 0.55 |
| ▸ | APLNR | P35414 | 3/20 | 0.48 |
| ▸ | GNRHR | P30968 | 2/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9630723 | 0.93 | NMUR2 (0.55) | EPHA2NMUR2NMUR1APLNRGNRHR | |
| SCHEMBL9630682 | 0.88 | NMUR2 (0.57) | EPHA2NMUR2NMUR1APLNRGNRHR | |
| SCHEMBL9629910 | 0.88 | NMUR2 (0.63) | EPHA2NMUR2NMUR1APLNR | |
| SCHEMBL9629930 | 0.88 | NMUR2 (0.56) | EPHA2NMUR2NMUR1APLNRGNRHR | |
| SCHEMBL9629866 | 0.87 | NMUR2 (0.58) | EPHA2NMUR2NMUR1APLNRGNRHR | |
| SCHEMBL10589391 | 0.85 | EPHA2 (0.51) | EPHA2NMUR2NMUR1APLNROPRM1 | |
| SCHEMBL9852750 | 0.84 | NPY4R (0.58) | EPHA2NMUR2NMUR1OPRM1KISS1R | |
| SCHEMBL9631369 | 0.82 | GNRHR (0.56) | EPHA2NMUR2NMUR1GNRHRKISS1R | |
| SCHEMBL10588690 | 0.82 | NPY4R (0.61) | NMUR2NMUR1 | |
| SCHEMBL10586963 | 0.81 | NMUR2 (0.57) | EPHA2NMUR2NMUR1GNRHRDRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5140009-A | Stable against proteolytic enzymes; anticarcinogenic agents; urogenital disorders | TAP PHARMACEUTICALS, INC. (US) | 1992-08-18 | — | — | US | disclosed |