Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 2/20 | 0.51 |
| ▸ | NMUR2 | Q9GZQ4 | 5/20 | 0.50 |
| ▸ | NMUR1 | Q9HB89 | 5/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.46 |
| ▸ | NTSR2 | O95665 | 3/20 | 0.45 |
| ▸ | NTSR1 | P30989 | 3/20 | 0.45 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | NPY4R | P50391 | 3/20 | 0.45 |
| ▸ | NPY1R | P25929 | 2/20 | 0.45 |
| ▸ | NPY2R | P49146 | 2/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.45 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.45 |
| ▸ | APLNR | P35414 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9630723 | 0.92 | NMUR2 (0.55) | EPHA2NMUR2NMUR1OPRM1APLNR | |
| SCHEMBL9630682 | 0.86 | NMUR2 (0.57) | EPHA2NMUR2NMUR1OPRM1APLNR | |
| SCHEMBL9629930 | 0.86 | NMUR2 (0.56) | EPHA2NMUR2NMUR1OPRD1OPRM1 | |
| SCHEMBL9727482 | 0.85 | EPHA2 (0.55) | EPHA2NMUR2NMUR1OPRM1APLNR | |
| SCHEMBL9631369 | 0.84 | GNRHR (0.56) | EPHA2NMUR2NMUR1CXCR4 | |
| SCHEMBL9629910 | 0.81 | NMUR2 (0.63) | EPHA2NMUR2NMUR1OPRD1NPY4R | |
| SCHEMBL10586963 | 0.81 | NMUR2 (0.57) | EPHA2NMUR2NMUR1OPRM1NPY4R | |
| SCHEMBL9629866 | 0.80 | NMUR2 (0.58) | EPHA2NMUR2NMUR1OPRM1APLNR | |
| SCHEMBL9632015 | 0.80 | EPHA2 (0.56) | EPHA2NMUR2NMUR1OPRM1 | |
| SCHEMBL9630737 | 0.80 | KISS1R (0.57) | EPHA2CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328089-A2 | Reduced size LHRH analogs | ABBOTT LABORATORIES (US) | 1989-08-16 | — | — | EP | disclosed |