Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | F13A1 | P00488 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28306232 | 0.98 | HDAC3 (0.44) | HDAC3MAPK1ADRA1AHDAC4SLC6A3 | |
| SCHEMBL28142282 | 0.89 | KEAP1 (0.42) | HDAC3MAPK1ADRA1AHDAC4SLC6A3 | |
| SCHEMBL234448 | 0.75 | ACHE (0.40) | CDC25ACDC25BCDC25C | |
| SCHEMBL6544586 | 0.73 | ACHE (0.47) | CDC25ACDC25BCDC25C | |
| SCHEMBL2185936 | 0.72 | ACHE (0.50) | CDC25ACDC25BCDC25C | |
| SCHEMBL4372749 | 0.72 | ACHE (0.50) | CDC25ACDC25BCDC25C | |
| SCHEMBL6544689 | 0.72 | ACHE (0.50) | CDC25ACDC25BCDC25C | |
| SCHEMBL6543575 | 0.72 | ACHE (0.50) | CDC25ACDC25BCDC25C | |
| SCHEMBL8922171 | 0.72 | ACHE (0.50) | CDC25ACDC25BCDC25C | |
| SCHEMBL6413040 | 0.72 | ACHE (0.50) | CDC25ACDC25BCDC25C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109999183-B | Nano-clustering enzyme containing hypoxia activated prodrug and preparation method and application thereof | 中国科学技术大学 | 2021-03-09 | — | — | CN | disclosed |
| CN-109999183-B | Nano-clustering enzyme containing hypoxia activated prodrug and preparation method and application thereof | 中国科学技术大学 | 2021-03-09 | — | — | CN | disclosed |
| CN-109999183-A | A kind of nano-cluster enzyme and its preparation method and application containing weary oxygen activation prodrug | 中国科学技术大学 | 2019-07-12 | — | — | CN | disclosed |
| CN-109999183-A | A kind of nano-cluster enzyme and its preparation method and application containing weary oxygen activation prodrug | 中国科学技术大学 | 2019-07-12 | — | — | CN | disclosed |
| CN-106633015-B | The polyethylene glycol of bridging-aliphatic poly ester block copolymer, preparation method, intermediate and purposes | 中国科学技术大学 | 2019-03-29 | — | — | CN | disclosed |
| CN-106633015-A | Bridged polyethylene glycol-aliphatic polyester segmented copolymer, preparation method thereof, intermediate and purpose thereof | 中国科学技术大学 | 2017-05-10 | — | — | CN | disclosed |
| US-5140013-A | Shelf life; polymerization inhibition; nontoxic; side effects reduction | UNIVERSITE LAVAL (CA) | 1992-08-18 | — | — | US | disclosed |
| WO-1991008775-A2 | MALEIC ANHYDRIDE DERIVATIVES USED AS CONJUGATION AGENTS OF ANTI-TUMOR AGENTS ON DESIRED CARRIERS | UNIVERSITE LAVAL (CA) | 1991-06-27 | — | — | WO | disclosed |