Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 4/20 | 0.66 |
| ▸ | ICAM1 | P05362 | 4/20 | 0.66 |
| ▸ | ITGAL | P20701 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | ACE | P12821 | 4/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727891 | 1.00 | ITGB2 (0.66) | ITGB2ICAM1ITGALMEN1KMT2A | |
| SCHEMBL2959306 | 0.92 | ALOX15 (0.64) | ITGB2ICAM1ITGALMEN1KMT2A | |
| SCHEMBL2956712 | 0.92 | ALOX15 (0.64) | ITGB2ICAM1ITGALMEN1KMT2A | |
| SCHEMBL28587519 | 0.92 | ALOX15 (0.64) | ITGB2ICAM1ITGALMEN1KMT2A | |
| SCHEMBL9728039 | 0.91 | ITGB2 (0.56) | ITGB2ICAM1ITGALMEN1KMT2A | |
| SCHEMBL15143015 | 0.89 | ITGB2 (0.59) | ITGB2ICAM1ITGALMEN1KMT2A | |
| SCHEMBL15145377 | 0.87 | ALOX15 (0.58) | ITGB2ICAM1ITGALMEN1KMT2A | |
| SCHEMBL15145396 | 0.87 | KMT2A (0.74) | ITGB2ICAM1ITGALMEN1KMT2A | |
| SCHEMBL1233383 | 0.86 | KMT2A (0.68) | ITGB2ICAM1ITGALMEN1KMT2A | |
| SCHEMBL1233499 | 0.86 | KMT2A (0.68) | ITGB2ICAM1ITGALMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5140009-A | Stable against proteolytic enzymes; anticarcinogenic agents; urogenital disorders | TAP PHARMACEUTICALS, INC. (US) | 1992-08-18 | — | — | US | disclosed |
| EP-0417454-A2 | Reduced size LHRH analogs | ABBOTT LABORATORIES (US) | 1991-03-20 | — | — | EP | disclosed |