Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | LTA4H | P09960 | 1/20 | 0.64 |
| ▸ | ACE | P12821 | 5/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.62 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.62 |
| ▸ | ITGAL | P20701 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.61 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.61 |
| ▸ | PPARG | P37231 | 1/20 | 0.61 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28587519 | 1.00 | ALOX15 (0.64) | ALOX15LTA4HACEKMT2AITGB2 | |
| SCHEMBL2956712 | 1.00 | ALOX15 (0.64) | ALOX15LTA4HACEKMT2AITGB2 | |
| SCHEMBL1233499 | 0.93 | KMT2A (0.68) | ALOX15LTA4HACEKMT2AITGB2 | |
| SCHEMBL1233383 | 0.93 | KMT2A (0.68) | ALOX15LTA4HACEKMT2AITGB2 | |
| SCHEMBL9727576 | 0.92 | ITGB2 (0.66) | ALOX15ACEKMT2AITGB2ICAM1 | |
| SCHEMBL9727891 | 0.92 | ITGB2 (0.66) | ALOX15ACEKMT2AITGB2ICAM1 | |
| SCHEMBL2489043 | 0.91 | KMT2A (0.72) | ALOX15LTA4HACEKMT2AITGB2 | |
| SCHEMBL15145377 | 0.90 | ALOX15 (0.58) | ALOX15LTA4HACEKMT2AITGB2 | |
| SCHEMBL15145396 | 0.90 | KMT2A (0.74) | ALOX15ACEKMT2AITGB2ICAM1 | |
| SCHEMBL21203216 | 0.89 | ACE (0.58) | ALOX15LTA4HACEKMT2AITGB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7767692-B2 | 1-amidomethylcarbonyl-piperidine compounds, methods and intermediate products for the production thereof and pharmaceutical formulations containing said compounds | SOLVAY PHARMACEUTICALS GMBH (DE) | 2010-08-03 | — | — | US | disclosed |
| EP-1392679-B1 | NOVEL 1-AMIDOMETHYLCARBONYL-PIPERIDINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND MEDICAMENT CONTAINING SAID COMPOUNDS | SOLVAY PHARM GMBH (DE) | 2005-11-02 | — | — | EP | disclosed |
| US-20040152732-A1 | 1-amidomethylcarbonyl-piperidine compounds, methods and intermediate products for the production thereof and pharmaceutical formulations containing said compounds | SOLVAY PHARMACEUTICALS GMBH (DE) | 2004-08-05 | — | — | US | disclosed |
| EP-1392679-A1 | NOVEL 1-AMIDOMETHYLCARBONYL-PIPERIDINE DERIVATIVES, METHOD AND INTERMEDIATE PRODUCTS FOR THE PRODUCTION THEREOF AND MEDICAMENT CONTAINING SAID COMPOUNDS | Solvay Pharmaceuticals GmbH (DE) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002092592-A1 | NOVEL 1-AMIDOMETHYLCARBONYL-PIPERIDINE DERIVATIVES, METHOD AND INTERMEDIATE PRODUCTS FOR THE PRODUCTION THEREOF AND MEDICAMENT CONTAINING SAID COMPOUNDS | SOLVAY PHARMACEUTICALS GMBH (DE) | 2002-11-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152732-A1 | 1-amidomethylcarbonyl-piperidine compounds, methods and intermediate products for the production thereof and pharmaceutical formulations containing said compounds | MLNR, GIPR, MLN | ALOX15 2953/4885LTA4H 593/4885ACE 2340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.