Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | PLAT | P00750 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9727329 | 0.85 | ALDH1A1 (0.52) | TSHRMEN1KMT2AALDH1A1FKBP1A | |
| SCHEMBL9727543 | 0.81 | ALDH1A1 (0.55) | TSHRMAPK1RECQLMEN1KMT2A | |
| SCHEMBL9727391 | 0.78 | MEN1 (0.47) | TSHRMAPK1RECQLMEN1KMT2A | |
| SCHEMBL9727268 | 0.78 | MEN1 (0.47) | TSHRMAPK1RECQLMEN1KMT2A | |
| SCHEMBL9727452 | 0.78 | TSHR (0.50) | TSHRMAPK1RECQLMEN1KMT2A | |
| SCHEMBL9727236 | 0.77 | TSHR (0.57) | TSHRMAPK1RECQLMEN1KMT2A | |
| SCHEMBL9727475 | 0.76 | ALDH1A1 (0.52) | TSHRMEN1KMT2AALDH1A1FKBP1A | |
| SCHEMBL9727217 | 0.73 | ALDH1A1 (0.55) | TSHRMAPK1RECQLMEN1KMT2A | |
| SCHEMBL9727251 | 0.73 | ALDH1A1 (0.45) | TSHRMAPK1RECQLMEN1KMT2A | |
| SCHEMBL9727445 | 0.73 | TSHR (0.55) | TSHRMAPK1RECQLMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091537-A | Acylamino acid ester derivatives; insecticide, fungicide, herbicide, acaricide, and antimycotic agent | BAYER AKTIENGESELLSCHAFT (DE) | 1992-02-25 | — | — | US | disclosed |
| US-4985063-A | INSECTICIDES, MITICIDES, HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-15 | — | — | US | disclosed |