SCHEMBL9727329

SCHEMBL9727329

COC(=O)C1CCCN1C(=O)C(Cl)c1cc(Cl)ccc1Cl

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
PEPD P12955 3/20 0.43
XPNPEP1 Q9NQW7 2/20 0.43
TSHR P16473 1/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
FKBP1A P62942 1/20 0.42
F2 P00734 5/20 0.41
PRSS1 P07477 2/20 0.41
F10 P00742 1/20 0.41
PRSS2 P07478 1/20 0.41
PRSS3 P35030 1/20 0.41
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
ENPP2 Q13822 1/20 0.40
PLAT P00750 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9727475 0.91 ALDH1A1 (0.52) ALDH1A1PEPDXPNPEP1TSHRMEN1
SCHEMBL9727523 0.86 ALDH1A1 (0.46) ALDH1A1PEPDXPNPEP1FKBP1ACYP1A2
SCHEMBL9727578 0.85 TSHR (0.53) ALDH1A1TSHRMEN1KMT2AFKBP1A
SCHEMBL9727278 0.83 TSHR (0.54) ALDH1A1PEPDXPNPEP1TSHRFKBP1A
SCHEMBL9727485 0.80 PEPD (0.44) ALDH1A1PEPDXPNPEP1KMT2ASMN1; SMN2
SCHEMBL9727508 0.76 ALDH1A1 (0.45) ALDH1A1PEPDXPNPEP1CYP1A2CYP3A4
SCHEMBL15053502 0.75 ALDH1A1 (0.52) ALDH1A1TSHRKMT2AFKBP1AENPP2
SCHEMBL15053501 0.75 ALDH1A1 (0.52) ALDH1A1TSHRKMT2AFKBP1AENPP2
SCHEMBL9727271 0.74 ALDH1A1 (0.61) ALDH1A1KMT2AENPP2
SCHEMBL26210944 0.73 ALDH1A1 (0.47) ALDH1A1TSHRKMT2AFKBP1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5142065-A Intermediates for herbicides, fungicides, miticides and insecticides BAYER AKTIENGESELLSCHAFT (DE) 1992-08-25 US disclosed
US-5091537-A Acylamino acid ester derivatives; insecticide, fungicide, herbicide, acaricide, and antimycotic agent BAYER AKTIENGESELLSCHAFT (DE) 1992-02-25 US disclosed
US-4985063-A INSECTICIDES, MITICIDES, HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1991-01-15 US disclosed