Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.70 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.70 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10932447 | 0.89 | CHRM2 (0.75) | CHRM2CHRM4CHRM1CYP1A2CYP3A4 | |
| SCHEMBL10930585 | 0.89 | CHRM2 (0.75) | CHRM2CHRM4CHRM1CYP1A2CYP3A4 | |
| SCHEMBL10508289 | 0.88 | CHRM2 (0.76) | CHRM2CHRM4CHRM1CYP1A2CYP3A4 | |
| SCHEMBL10514622 | 0.88 | CHRM2 (0.74) | CHRM2CHRM4CHRM1CYP1A2CYP3A4 | |
| SCHEMBL9824471 | 0.88 | CHRM2 (0.71) | CHRM2CHRM4CHRM1CYP1A2CYP3A4 | |
| SCHEMBL10520897 | 0.87 | CHRM2 (0.61) | CHRM2CHRM4CHRM1CYP1A2CYP3A4 | |
| SCHEMBL9728337 | 0.87 | CHRM2 (0.75) | CHRM2CHRM4CHRM1CYP1A2CYP3A4 | |
| SCHEMBL9727711 | 0.87 | CHRM2 (0.75) | CHRM2CHRM4CHRM1CYP1A2CHRM3 | |
| SCHEMBL9674004 | 0.87 | — | — | |
| SCHEMBL9728148 | 0.87 | CHRM2 (0.81) | CHRM2CHRM4CHRM1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175158-A | CONDENSED DIAZEPINONES, PROCESSES FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS | DR. KARL THOMAE, GMBH (DE) | 1992-12-29 | — | — | US | disclosed |
| EP-0312895-A2 | Condensed diazepinones, process for their preparation and medicament containing them | Dr. Karl Thomae GmbH (DE) | 1989-04-26 | — | — | EP | disclosed |