Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | MGAM | O43451 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | SI | P14410 | 3/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8036010 | 0.91 | KDM4E (0.53) | CYP19A1MGAMGAASIMGAM2 | |
| SCHEMBL4114408 | 0.85 | KDM4E (0.49) | MGAMGAASIMGAM2MTNR1A | |
| SCHEMBL9856070 | 0.83 | MGAM (0.55) | MGAMGAASIMGAM2MTNR1A | |
| SCHEMBL14012896 | 0.83 | MAOB (0.52) | GAAMTNR1AKDM4EALDH1A1MAOB | |
| SCHEMBL20024720 | 0.82 | MAPT (0.55) | CYP19A1MTNR1AKDM4EALDH1A1MAOB | |
| SCHEMBL670129 | 0.82 | PPARD (0.49) | GAAMTNR1AKDM4EALDH1A1MAOB | |
| SCHEMBL9856624 | 0.82 | KDM4E (0.46) | CYP19A1MGAMGAASIMGAM2 | |
| SCHEMBL11555831 | 0.82 | MAOB (0.53) | GAAMTNR1AKDM4EALDH1A1MAOB | |
| SCHEMBL791805 | 0.81 | LMNA (0.53) | MTNR1AKDM4EALDH1A1MAOBMTNR1B | |
| SCHEMBL11269821 | 0.81 | PPARG (0.44) | MTNR1AALDH1A1MAOBAOC3MTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091533-A | Treating allergies, cardiovascular disorders, inflammation | MERCK FROSST CANADA, INC. (CA) | 1992-02-25 | — | — | US | disclosed |
| EP-0447189-A1 | 5-Hydroxy-2,3-dihydrobenzofuran analogs as leukotriene biosynthesis inhibitors | MERCK FROSST CANADA INC. (CA) | 1991-09-18 | — | — | EP | disclosed |
| US-4156725-A | MICROBIOCIDES | BURROUGHS WELLCOME CO. (US) | 1979-05-29 | — | — | US | disclosed |