Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | NDUFS8 | O00217 | 1/20 | 0.44 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.44 |
| ▸ | NDUFAB1 | O14561 | 1/20 | 0.44 |
| ▸ | NDUFA1 | O15239 | 1/20 | 0.44 |
| ▸ | NDUFS4 | O43181 | 1/20 | 0.44 |
| ▸ | NDUFB5 | O43674 | 1/20 | 0.44 |
| ▸ | NDUFB3 | O43676 | 1/20 | 0.44 |
| ▸ | NDUFC1 | O43677 | 1/20 | 0.44 |
| ▸ | NDUFA2 | O43678 | 1/20 | 0.44 |
| ▸ | NDUFS5 | O43920 | 1/20 | 0.44 |
| ▸ | NDUFS7 | O75251 | 1/20 | 0.44 |
| ▸ | NDUFS2 | O75306 | 1/20 | 0.44 |
| ▸ | NDUFS6 | O75380 | 1/20 | 0.44 |
| ▸ | NDUFB1 | O75438 | 1/20 | 0.44 |
| ▸ | NDUFS3 | O75489 | 1/20 | 0.44 |
| ▸ | NDUFB6 | O95139 | 1/20 | 0.44 |
| ▸ | NDUFA3 | O95167 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8036010 | 0.89 | KDM4E (0.53) | KDM4EALDH1A1MTNR1ANDUFS8COXFA4 | |
| SCHEMBL4114408 | 0.83 | KDM4E (0.49) | KDM4EALDH1A1MTNR1ANDUFS8COXFA4 | |
| SCHEMBL9856070 | 0.82 | MGAM (0.55) | KDM4EALDH1A1MTNR1AGAALMNA | |
| SCHEMBL14012896 | 0.82 | MAOB (0.52) | KDM4EALDH1A1MTNR1AHTTGAA | |
| SCHEMBL9727736 | 0.82 | CYP19A1 (0.48) | KDM4EALDH1A1MTNR1AGAAMGAM | |
| SCHEMBL11555831 | 0.80 | MAOB (0.53) | KDM4EALDH1A1MTNR1AHTTGAA | |
| SCHEMBL20024720 | 0.80 | MAPT (0.55) | KDM4EALDH1A1MTNR1ANDUFS8COXFA4 | |
| SCHEMBL670129 | 0.80 | PPARD (0.49) | KDM4EALDH1A1MTNR1AHTTGAA | |
| SCHEMBL1135899 | 0.79 | NDUFS8 (0.49) | KDM4EALDH1A1MTNR1ANDUFS8COXFA4 | |
| SCHEMBL9262789 | 0.78 | ALDH1A1 (0.50) | KDM4EALDH1A1MTNR1AHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037991-A | Insecticides | SANDOZ LTD. (CH) | 1991-08-06 | — | — | US | disclosed |
| US-4968829-A | ANTHELMINTICS, PARASITICIDES, NEMATOCIDES | SANDOZ LTD. (CH) | 1990-11-06 | — | — | US | disclosed |