Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9199295 | 1.00 | MAPT (0.40) | MAPTALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL9202663 | 0.92 | MAPT (0.39) | MAPTALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL9199498 | 0.90 | MAPT (0.42) | MAPTALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL9728231 | 0.90 | MAPT (0.42) | MAPTALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL9728542 | 0.90 | MAPT (0.45) | MAPTALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL9728545 | 0.90 | MAPT (0.45) | MAPTALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL9199238 | 0.83 | MAPT (0.44) | MAPTALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL9208262 | 0.83 | ALDH1A1 (0.42) | MAPTALDH1A1HPGDPOLBATM | |
| SCHEMBL9727854 | 0.83 | ALDH1A1 (0.42) | MAPTALDH1A1HPGDPOLBATM | |
| SCHEMBL9728021 | 0.79 | ATM (0.43) | MAPTALDH1A1HPGDL3MBTL1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5122604-A | 2-(2-Carbonyl-substituted pyrrolidin-4-yl)carbapenems and -penems; microbiocides | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1992-06-16 | — | — | US | disclosed |
| US-4943569-A | B-lactam compounds | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1990-07-24 | — | — | US | disclosed |
| US-4933333-A | β-lactam compounds | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1990-06-12 | — | — | US | disclosed |
| EP-0126587-A1 | Carboxylic thio-pyrrolidinyl beta-lactam compounds and production thereof | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1984-11-28 | — | — | EP | disclosed |