Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 11/20 | 0.44 |
| ▸ | CTSK | P43235 | 11/20 | 0.44 |
| ▸ | CTSB | P07858 | 3/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9337445 | 0.89 | TSHR (0.42) | CTSSCTSKCTSBCTSLPPARG | |
| SCHEMBL9335239 | 0.84 | PPARA (0.44) | CTSSCTSKCTSBCTSLPPARG | |
| SCHEMBL4864593 | 0.84 | PPARA (0.44) | CTSSCTSKCTSBCTSLPPARG | |
| SCHEMBL9334048 | 0.82 | KLK5 (0.42) | CTSSCTSKCTSBCTSLPPARG | |
| SCHEMBL9728488 | 0.81 | ACE (0.48) | CTSSCTSKCTSBCTSLPPARG | |
| SCHEMBL13970822 | 0.80 | CTSS (0.50) | CTSSCTSKCTSBCTSLPPARG | |
| SCHEMBL12194647 | 0.79 | CTSS (0.49) | CTSSCTSKCTSBCTSL | |
| SCHEMBL9335243 | 0.76 | PPID (0.43) | PPARA | |
| SCHEMBL11388207 | 0.74 | CTSS (0.74) | CTSSCTSKCTSBCTSLATM | |
| SCHEMBL431474 | 0.73 | CYP2C19 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169833-A | Analgesics | G. D. SEARLE & CO. (US) | 1992-12-08 | — | — | US | disclosed |