Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 16/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL432334 | 1.00 | CYP2C19 (0.38) | CYP2C19HIF1AKIF11HDAC3HDAC4 | |
| SCHEMBL431472 | 0.82 | CDC25A (0.39) | KIF11HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL432329 | 0.77 | LMNA (0.42) | KIF11 | |
| SCHEMBL431461 | 0.73 | KIF11 (0.46) | KIF11 | |
| SCHEMBL9728227 | 0.73 | CTSS (0.44) | — | |
| SCHEMBL433717 | 0.71 | CYP2C19 (0.42) | CYP2C19HIF1AKIF11HDAC3HDAC4 | |
| SCHEMBL433727 | 0.70 | MDM4 (0.48) | — | |
| SCHEMBL7762919 | 0.69 | CTH (0.35) | CYP2C19HIF1A | |
| SCHEMBL18160139 | 0.69 | KIF11 (0.45) | CYP2C19HIF1AKIF11HDAC3HDAC4 | |
| SCHEMBL4864593 | 0.69 | PPARA (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065367-A1 | Radioactively Labeled Substance | NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY (JP) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065367-A1 | Radioactively Labeled Substance | KIT, ABCG2, TK1 | CYP2C19 2093/4885HIF1A 1529/4885KIF11 2671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.