Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.54 |
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | CTSS | P25774 | 9/20 | 0.46 |
| ▸ | CTSK | P43235 | 8/20 | 0.46 |
| ▸ | CTSB | P07858 | 4/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | REN | P00797 | 1/20 | 0.41 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.41 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.41 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728261 | 1.00 | OPRM1 (0.54) | OPRM1CTSLCTSSCTSKCTSB | |
| SCHEMBL9727701 | 0.92 | OPRM1 (0.63) | OPRM1CTSLCTSSCTSKCTSB | |
| SCHEMBL9728253 | 0.90 | OPRM1 (0.59) | OPRM1CTSLCTSSCTSKCTSB | |
| SCHEMBL9499408 | 0.89 | CTSS (0.53) | CTSLCTSSCTSKCTSBPPARG | |
| SCHEMBL9499402 | 0.89 | CTSS (0.53) | CTSLCTSSCTSKCTSBPPARG | |
| SCHEMBL9728357 | 0.85 | OPRM1 (0.57) | OPRM1ACE | |
| SCHEMBL9728367 | 0.85 | OPRM1 (0.57) | OPRM1ACE | |
| SCHEMBL9727738 | 0.82 | OPRM1 (0.68) | OPRM1CTSLCTSSCTSKCTSB | |
| SCHEMBL9728033 | 0.80 | OPRM1 (0.66) | OPRM1 | |
| SCHEMBL9728154 | 0.80 | OPRM1 (0.66) | OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169833-A | Analgesics | G. D. SEARLE & CO. (US) | 1992-12-08 | — | — | US | disclosed |