Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 9/20 | 0.53 |
| ▸ | REN | P00797 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.50 |
| ▸ | ITGAV | P06756 | 1/20 | 0.50 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.50 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PEPD | P12955 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2422749 | 0.95 | ACE (0.48) | ACERENLMNAHSD17B10ITGB3 | |
| SCHEMBL2422744 | 0.95 | ACE (0.48) | ACERENLMNAHSD17B10ITGB3 | |
| SCHEMBL23793783 | 0.86 | KMT2A (0.46) | CYP2C19KDM4EF2KMT2AALDH1A1 | |
| SCHEMBL19347965 | 0.86 | KMT2A (0.46) | LMNACYP2C19F2KMT2AALDH1A1 | |
| SCHEMBL17285637 | 0.83 | ACE (0.51) | ACERENLMNAHSD17B10ITGB3 | |
| SCHEMBL9046806 | 0.83 | NPSR1 (0.55) | ACERENLMNAHSD17B10ITGB3 | |
| SCHEMBL9046814 | 0.83 | NPSR1 (0.55) | ACERENLMNAHSD17B10ITGB3 | |
| SCHEMBL6407009 | 0.83 | ACE (0.60) | ACERENLMNAHSD17B10ITGB3 | |
| SCHEMBL4728479 | 0.83 | THRB (0.49) | ACERENLMNAHSD17B10ITGB3 | |
| SCHEMBL4902901 | 0.82 | RAB9A (0.56) | ACERENLMNAHSD17B10ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5140009-A | Stable against proteolytic enzymes; anticarcinogenic agents; urogenital disorders | TAP PHARMACEUTICALS, INC. (US) | 1992-08-18 | — | — | US | claimed |