Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | KIF11 | P52732 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.43 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.43 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.43 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9185909 | 0.87 | CYP1A2 (0.56) | HDAC1HDAC6CA1CA2CA9 | |
| SCHEMBL31434967 | 0.87 | CYP1A2 (0.56) | HDAC1HDAC6CA1CA2CA9 | |
| SCHEMBL16799522 | 0.86 | SMN1; SMN2 (0.59) | HDAC1HDAC6CA1CA2CA9 | |
| SCHEMBL5524582 | 0.83 | HDAC1 (0.55) | HDAC1HDAC6CA1CA2CA9 | |
| SCHEMBL29739646 | 0.83 | HDAC1 (0.55) | HDAC1HDAC6CA1CA2CA9 | |
| SCHEMBL6693771 | 0.81 | CYP1A2 (0.48) | HDAC1HDAC6CA1CA2CA9 | |
| SCHEMBL27563485 | 0.78 | HDAC1 (0.50) | HDAC1HDAC6CA1CA2CA9 | |
| SCHEMBL30148008 | 0.75 | SMN1; SMN2 (0.67) | HDAC1HDAC6CA1CA2CA9 | |
| SCHEMBL6694651 | 0.75 | SMN1; SMN2 (0.67) | HDAC1HDAC6CA1CA2CA9 | |
| SCHEMBL9728256 | 0.75 | HDAC1 (0.43) | HDAC1HDAC6CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0246061-B1 | A BENZOYLUREA DERIVATIVE AND ITS PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-03-18 | — | — | EP | disclosed |