Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14822787 | 0.83 | ESR1 (0.47) | CYP1A2CYP2C9CYP2C19ESR1SMN1; SMN2 | |
| SCHEMBL9728267 | 0.81 | HDAC1 (0.53) | CYP1A2CYP2C9CYP2C19ESR1SMN1; SMN2 | |
| SCHEMBL5353233 | 0.76 | PKM (0.55) | SMN1; SMN2NPC1POLBMAPTRAB9A | |
| SCHEMBL11623168 | 0.75 | MAPT (0.40) | SMN1; SMN2POLBMAPTPKMMEN1 | |
| SCHEMBL7871930 | 0.75 | NPC1 (0.61) | SMN1; SMN2NPC1POLBMAPTRAB9A | |
| SCHEMBL17681595 | 0.75 | CYP2C19 (0.65) | CYP1A2CYP2C9CYP2C19ESR1MAPT | |
| SCHEMBL3253108 | 0.74 | HPGD (0.42) | CYP1A2CYP2C9CYP2C19MAPTPKM | |
| SCHEMBL13905148 | 0.74 | CYP1A2 (0.50) | CYP1A2CYP2C9CYP2C19ESR1SMN1; SMN2 | |
| SCHEMBL16386159 | 0.74 | RAB9A (0.47) | ESR1NPC1POLBMAPTRAB9A | |
| SCHEMBL9861532 | 0.74 | ESR1 (0.65) | ESR1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362369-B1 | — | — | None | — | — | US | disclosed |
| EP-0936212-B1 | Fluorine-containing aniline compounds | NIHON NOHYAKU CO LTD (JP) | 2004-04-21 | — | — | EP | disclosed |
| US-6559341-B2 | Phthalic acid diamide derivatives, fluorine-containing aniline compounds as starting material, agricultural and horticultural insecticides, and a method for application of the insecticides | NIHON NOHYAKU CO., LTD. (JP) | 2003-05-06 | — | — | US | disclosed |
| US-20030055287-A1 | Phthalic acid diamide derivatives, fluorine-containing aniline compounds as starting material, agricultural and horticultural insecticides, and a method for application of the insecticides | AIR MOTION TECHNOLOGIES, LLC | 2003-03-20 | — | — | US | disclosed |
| US-6362369-B2 | CONTROLLING INSECTS IN CROPS | NIHON NOHYAKU CO., LTD. (JP) | 2002-03-26 | — | — | US | disclosed |
| US-20010041814-A1 | PHTHALIC ACID DIAMIDE DERIVATIVES FLUORINE-CONTAINING ANILINE COMPOUNDS AS STARTING MATERIAL, AGRICULTURAL AND HORTICULTURAL INSECTICIDES, AND A METHOD FOR APPLICATION OF THE INSECTICIDES | NIHON NOHYAKU CO., LTD. (JP) | 2001-11-15 | — | — | US | disclosed |
| EP-0936212-A1 | Fluorine-containing aniline compounds | NIHON NOHYAKU CO., LTD. (JP) | 1999-08-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010041814-A1 | PHTHALIC ACID DIAMIDE DERIVATIVES FLUORINE-CONTAINING ANILINE COMPOUNDS AS STARTING MATERIAL, AGRICULTURAL AND HORTICULTURAL INSECTICIDES, AND A METHOD FOR APPLICATION OF THE INSECTICIDES | DDT, AFF1, BCL2L2 | CYP1A2 892/4885CYP2C9 2305/4885CYP2C19 3796/4885 |
| US-20030055287-A1 | Phthalic acid diamide derivatives, fluorine-containing aniline compounds as starting material, agricultural and horticultural insecticides, and a method for application of the insecticides | DDT, BCL2A1, BCL2L2 | CYP1A2 826/4885CYP2C9 2212/4885CYP2C19 3856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.