Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 5/20 | 0.34 |
| ▸ | BTK | Q06187 | 3/20 | 0.34 |
| ▸ | LYN | P07948 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | TSHR | P16473 | 5/20 | 0.33 |
| ▸ | KDR | P35968 | 4/20 | 0.33 |
| ▸ | TEK | Q02763 | 4/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728689 | 0.79 | BCL2 (0.33) | ALDH1A1TSHRNPSR1HTTSMN1; SMN2 | |
| SCHEMBL9729385 | 0.78 | KDM5A (0.32) | KDM5A | |
| SCHEMBL9728513 | 0.77 | TSHR (0.36) | ALDH1A1TSHRNPSR1HTTSMN1; SMN2 | |
| SCHEMBL9728650 | 0.69 | BCL2 (0.36) | ALDH1A1TSHRNPSR1SMN1; SMN2LMNA | |
| SCHEMBL9729023 | 0.68 | BCL2 (0.36) | LMNA | |
| SCHEMBL9637989 | 0.63 | MAPT (0.34) | HRH3ALDH1A1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL9637947 | 0.63 | NPY5R (0.35) | BTKHTTNPC1RAB9AMEN1 | |
| SCHEMBL5076801 | 0.61 | BCL2 (0.57) | ALDH1A1TSHRHTTHPGDLMNA | |
| SCHEMBL4360185 | 0.61 | MEN1 (0.47) | ALDH1A1TSHRHTTNPC1RAB9A | |
| SCHEMBL9368279 | 0.61 | BCL2 (0.41) | ALDH1A1TSHRHTTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0406163-A1 | Thioxotetrazolines | CIBA-GEIGY AG (CH) | 1991-01-02 | — | — | EP | claimed |
| US-5138068-A | Pesticide | CIBA-GEIGY CORPORATION (US) | 1992-08-11 | — | — | US | disclosed |
| US-5066667-A | Controlling insects and arachnids | CIBA-GEIGY CORPORATION (US) | 1991-11-19 | — | — | US | disclosed |
| EP-0406163-A1 | Thioxotetrazolines | CIBA-GEIGY AG (CH) | 1991-01-02 | — | — | EP | disclosed |