Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 4/20 | 0.34 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.34 |
| ▸ | NTRK2 | Q16620 | 3/20 | 0.34 |
| ▸ | IGF1R | P08069 | 2/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.34 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 3/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728529 | 0.84 | XIAP (0.36) | THRB | |
| SCHEMBL9728104 | 0.80 | DAO (0.40) | LMNAMGLLPTGS1FAAH | |
| SCHEMBL9728650 | 0.78 | BCL2 (0.36) | BCL2MCL1LMNAKDM5BMGLL | |
| SCHEMBL8600506 | 0.76 | MGLL (0.49) | MGLLNTRK1NTRK2IGF1RFGFR1 | |
| SCHEMBL9728689 | 0.75 | BCL2 (0.33) | BCL2MCL1MGLLPTGS1FAAH | |
| SCHEMBL9728513 | 0.71 | TSHR (0.36) | BCL2MCL1LMNAMGLLMDM2 | |
| SCHEMBL18504314 | 0.69 | NOTUM (0.43) | BCL2MCL1FGFR1MDM2 | |
| SCHEMBL9728279 | 0.68 | LCK (0.34) | LMNA | |
| SCHEMBL5076801 | 0.67 | BCL2 (0.57) | BCL2MCL1LMNATHRBPTGS1 | |
| SCHEMBL4360185 | 0.67 | MEN1 (0.47) | BCL2MCL1PTGS1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5138068-A | Pesticide | CIBA-GEIGY CORPORATION (US) | 1992-08-11 | — | — | US | claimed |