Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 2/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9729385 | 0.86 | KDM5A (0.32) | — | |
| SCHEMBL9728650 | 0.85 | BCL2 (0.36) | BCL2MCL1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL9728513 | 0.82 | TSHR (0.36) | BCL2MCL1ALDH1A1HPGDALOX12 | |
| SCHEMBL9729023 | 0.75 | BCL2 (0.36) | BCL2MCL1PTGS1FAAHMGLL | |
| SCHEMBL9728307 | 0.71 | TSHR (0.50) | ALDH1A1HPGDTSHRNPSR1PTGS1 | |
| SCHEMBL4360185 | 0.66 | MEN1 (0.47) | BCL2MCL1ALDH1A1HPGDALOX12 | |
| SCHEMBL5076801 | 0.66 | BCL2 (0.57) | BCL2MCL1ALDH1A1HPGDALOX12 | |
| SCHEMBL9368279 | 0.65 | BCL2 (0.41) | BCL2MCL1ALDH1A1HPGDALOX12 | |
| SCHEMBL9729088 | 0.65 | CRHBP (0.34) | ALDH1A1SMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9364864 | 0.65 | MEN1 (0.50) | BCL2MCL1ALDH1A1HPGDALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0406163-A1 | Thioxotetrazolines | CIBA-GEIGY AG (CH) | 1991-01-02 | — | — | EP | claimed |
| US-5138068-A | Pesticide | CIBA-GEIGY CORPORATION (US) | 1992-08-11 | — | — | US | disclosed |
| US-5066667-A | Controlling insects and arachnids | CIBA-GEIGY CORPORATION (US) | 1991-11-19 | — | — | US | disclosed |
| EP-0406163-A1 | Thioxotetrazolines | CIBA-GEIGY AG (CH) | 1991-01-02 | — | — | EP | disclosed |