Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PPIA | P62937 | 1/20 | 0.39 |
| ▸ | IL2 | P60568 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728803 | 0.93 | MEN1 (0.52) | MEN1KMT2AATMUSP2MAPT | |
| SCHEMBL9728475 | 0.90 | MEN1 (0.39) | MEN1KMT2AATMUSP2MAPT | |
| SCHEMBL352658 | 0.87 | MEN1 (0.54) | MEN1KMT2AATMUSP2MAPT | |
| SCHEMBL29608194 | 0.87 | MEN1 (0.54) | MEN1KMT2AATMUSP2MAPT | |
| SCHEMBL9727918 | 0.83 | MEN1 (0.50) | MEN1KMT2AATMUSP2MAPT | |
| SCHEMBL9729542 | 0.82 | RAB9A (0.41) | MEN1KMT2AATMUSP2MAPT | |
| SCHEMBL9728416 | 0.80 | KMT2A (0.59) | MEN1KMT2AATMUSP2MAPT | |
| SCHEMBL6503970 | 0.80 | KMT2A (0.47) | MEN1KMT2AATMUSP2MAPT | |
| SCHEMBL8657856 | 0.79 | KMT2A (0.59) | MEN1KMT2AATMMAPTNPC1 | |
| SCHEMBL10606310 | 0.78 | MEN1 (0.52) | MEN1KMT2AATMUSP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0246061-B1 | A BENZOYLUREA DERIVATIVE AND ITS PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-03-18 | — | — | EP | disclosed |