Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | SMO | Q99835 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL874173 | 0.87 | KDM4E (0.77) | KDM4EMAPK1HSD17B10ALDH1A1KMT2A | |
| SCHEMBL9728550 | 0.82 | KDM4E (0.56) | EPHX1KDM4EMAPK1ALDH1A1KMT2A | |
| SCHEMBL9728096 | 0.80 | EPHX1 (0.66) | EPHX1KDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL11492739 | 0.80 | SMO (0.67) | EPHX1ALDH1A1MAPTHPGDALOX12 | |
| SCHEMBL9728074 | 0.79 | ALDH1A1 (0.70) | EPHX1KDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL10221631 | 0.78 | KDM4E (0.63) | KDM4EMAPK1HSD17B10ALDH1A1KMT2A | |
| SCHEMBL16119683 | 0.78 | EPHX1 (0.81) | EPHX1KDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL7479676 | 0.77 | KDM4E (0.65) | KDM4EMAPK1HSD17B10ALDH1A1KMT2A | |
| SCHEMBL20993621 | 0.77 | KDM4E (0.51) | KDM4EMAPK1HSD17B10ALDH1A1KMT2A | |
| SCHEMBL9728350 | 0.77 | ALDH1A1 (0.70) | KDM4EALDH1A1KMT2AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5001157-A | Substituted N-[[2-(aminocarbonyl)phenylamino]thioxomethyl]benzamides | AMERICAN CYANAMID COMPANY (US) | 1991-03-19 | — | — | US | claimed |
| US-5084457-A | Cognition activators and nervous system disorders | AMERICAN CYANAMID COMPANY (US) | 1992-01-28 | — | — | US | disclosed |
| US-5001157-A | Substituted N-[[2-(aminocarbonyl)phenylamino]thioxomethyl]benzamides | AMERICAN CYANAMID COMPANY (US) | 1991-03-19 | — | — | US | disclosed |