Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | PLK1 | P53350 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728074 | 0.83 | ALDH1A1 (0.70) | KDM4EEPHX1ALDH1A1MEN1KMT2A | |
| SCHEMBL9728446 | 0.82 | EPHX1 (0.63) | KDM4EEPHX1ALDH1A1MEN1KMT2A | |
| SCHEMBL9728096 | 0.82 | EPHX1 (0.66) | KDM4EEPHX1ALDH1A1MEN1KMT2A | |
| SCHEMBL6118209 | 0.77 | EPHX1 (0.78) | KDM4EEPHX1ALDH1A1MEN1KMT2A | |
| SCHEMBL5713502 | 0.74 | NPC1 (0.72) | KDM4EEPHX1ALDH1A1MAPTALOX12 | |
| SCHEMBL14162005 | 0.74 | MEN1 (0.74) | KDM4EEPHX1ALDH1A1MEN1KMT2A | |
| SCHEMBL8612483 | 0.74 | EPHX1 (0.77) | KDM4EEPHX1ALDH1A1MEN1KMT2A | |
| SCHEMBL11157014 | 0.74 | EPHX1 (0.56) | KDM4EEPHX1ALDH1A1MEN1KMT2A | |
| SCHEMBL9728569 | 0.73 | ALDH1A1 (0.74) | KDM4EEPHX1ALDH1A1MEN1KMT2A | |
| SCHEMBL18343780 | 0.73 | EPHX1 (0.62) | KDM4EEPHX1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084457-A | Cognition activators and nervous system disorders | AMERICAN CYANAMID COMPANY (US) | 1992-01-28 | — | — | US | disclosed |
| US-5001157-A | Substituted N-[[2-(aminocarbonyl)phenylamino]thioxomethyl]benzamides | AMERICAN CYANAMID COMPANY (US) | 1991-03-19 | — | — | US | disclosed |