Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 5/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19214737 | 0.81 | FDPS (0.37) | NOS1TLR8TLR7 | |
| Methylamine SCHEMBL27939089 | 0.79 | TLR8 (0.48) | NOS1TLR8TLR7TBXAS1 | |
| SCHEMBL11438392 | 0.79 | TBXAS1 (0.47) | NOS1TLR8TLR7TBXAS1 | |
| SCHEMBL6114716 | 0.79 | TBXAS1 (0.47) | NOS1TLR8TLR7TBXAS1 | |
| SCHEMBL6114513 | 0.79 | TBXAS1 (0.47) | NOS1TLR8TLR7TBXAS1 | |
| SCHEMBL6114640 | 0.79 | TBXAS1 (0.47) | NOS1TLR8TLR7TBXAS1 | |
| SCHEMBL5691507 | 0.79 | TBXAS1 (0.47) | NOS1TLR8TLR7TBXAS1 | |
| SCHEMBL6114991 | 0.79 | TBXAS1 (0.47) | NOS1TLR8TLR7TBXAS1 | |
| SCHEMBL11440961 | 0.79 | TBXAS1 (0.47) | NOS1TLR8TLR7TBXAS1 | |
| SCHEMBL6114927 | 0.79 | TBXAS1 (0.47) | NOS1TLR8TLR7TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162360-A | Treating hypercholesterolemia and atherosclerosis; ACAT acyl-coenzyme A:-cholesterol acyltransferase | WARNER-LAMBERT COMPANY (US) | 1992-11-10 | — | — | US | disclosed |