Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ6 | P48051 | 2/20 | 0.49 |
| ▸ | KCNJ5 | P48544 | 2/20 | 0.49 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9729684 | 0.72 | — | — | |
| SCHEMBL9872794 | 0.71 | SOAT2 (0.46) | KCNJ6KCNJ5KCNJ3 | |
| SCHEMBL9728818 | 0.70 | SMN1; SMN2 (0.49) | — | |
| SCHEMBL9729291 | 0.69 | — | — | |
| SCHEMBL9729446 | 0.67 | MEN1 (0.44) | — | |
| SCHEMBL9873553 | 0.67 | SMN1; SMN2 (0.47) | — | |
| SCHEMBL7569944 | 0.67 | — | — | |
| SCHEMBL9729102 | 0.66 | — | — | |
| SCHEMBL9723419 | 0.66 | SOAT2 (0.51) | — | |
| SCHEMBL8984907 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162360-A | Treating hypercholesterolemia and atherosclerosis; ACAT acyl-coenzyme A:-cholesterol acyltransferase | WARNER-LAMBERT COMPANY (US) | 1992-11-10 | — | — | US | disclosed |