Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 9/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20376450 | 0.73 | S100A4 (0.40) | S100A4LMNA | |
| SCHEMBL20201784 | 0.73 | S100A4 (0.40) | S100A4LMNA | |
| SCHEMBL20207026 | 0.71 | S100A4 (0.53) | S100A4MEN1KMT2ALMNAPOLB | |
| SCHEMBL20201781 | 0.70 | HDAC4 (0.42) | S100A4 | |
| SCHEMBL10440488 | 0.68 | S100A4 (0.50) | S100A4MEN1KMT2ALMNAPOLB | |
| Anthraquinone SCHEMBL27605254 | 0.66 | PTPN1 (0.61) | S100A4SOAT1PTPN1NPC1GAA | |
| SCHEMBL16377312 | 0.66 | S100A4 (0.55) | S100A4MEN1KMT2ALMNAPOLB | |
| SCHEMBL22521864 | 0.65 | S100A4 (0.50) | S100A4LMNA | |
| SCHEMBL27314465 | 0.65 | MEN1 (0.50) | NPC1GAARAB9AMEN1KMT2A | |
| SCHEMBL15844488 | 0.65 | PTPN1 (0.44) | PTPN1NPC1GAARAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155106-A | Reduced side effects | TERUMO KABUSHIKI KAISHA (JP) | 1992-10-13 | — | — | US | disclosed |
| EP-0400144-A1 | CYSTEAMINE DERIVATIVES AND ANTI-RHEUMATIC AGENT CONTAINING SAME | TERUMO KABUSHIKI KAISHA (JP) | 1990-12-05 | — | — | EP | disclosed |