Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.31 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.31 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | TXN | P10599 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL437532 | 0.83 | AHR (0.38) | PTGS2NPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL2874737 | 0.81 | CYP1A2 (0.41) | TYMPPTGS2TSHRHSD17B10PTGS1 | |
| SCHEMBL1568008 | 0.79 | MAPK1 (0.34) | TP53 | |
| SCHEMBL10832478 | 0.79 | — | — | |
| SCHEMBL9731437 | 0.79 | PTGS2 (0.37) | PTGS2HSD17B10KDM4E | |
| SCHEMBL7803250 | 0.79 | KIF11 (0.41) | — | |
| SCHEMBL17514836 | 0.77 | NISCH (0.38) | NPC1RAB9ATP53SMN1; SMN2KDM4E | |
| SCHEMBL17514789 | 0.76 | — | — | |
| SCHEMBL7281497 | 0.75 | AHR (0.52) | NPC1RAB9ATP53TSHRHSD17B10 | |
| SCHEMBL1645683 | 0.75 | CA12 (0.41) | PTGS2NPC1RAB9ATP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5156669-A | Fungicides and plant growth regulators | BASF AKTIENGESELLSCHAFT (DE) | 1992-10-20 | — | — | US | disclosed |