Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.59 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.55 |
| ▸ | TUBB | P07437 | 1/20 | 0.55 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.55 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.55 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.55 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.55 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.55 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.55 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.55 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.55 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.55 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.55 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.55 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.55 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4257291 | 0.80 | CYP19A1 (0.65) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4262071 | 0.80 | MAPT (0.54) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL27900296 | 0.79 | TUBB1 (0.63) | TNFRSF1ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9729765 | 0.78 | ERN1 (0.50) | ALDH1A1MAPTKDM4EABCG2SMN1; SMN2 | |
| SCHEMBL7035797 | 0.78 | LMNA (0.56) | TUBB1KDM4ETDP1TRPA1POLB | |
| SCHEMBL7035796 | 0.78 | LMNA (0.56) | TUBB1KDM4ETDP1TRPA1POLB | |
| SCHEMBL29136488 | 0.76 | TUBB1 (0.69) | TNFRSF1ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29136491 | 0.76 | TUBB1 (0.69) | TNFRSF1ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL118593 | 0.76 | TUBB1 (0.69) | TNFRSF1ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL31317684 | 0.76 | PTPN1 (0.49) | TNFRSF1AALDH1A1MAPTKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5126444-A | Antibiotics | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-06-30 | — | — | US | disclosed |
| US-5064824-A | CEPHALOSPORIN COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-11-12 | — | — | US | disclosed |
| EP-0341910-A2 | Cephalosporins, process for their preparation, intermediates and pharmaceutical compositions | ZENECA LIMITED (GB) | 1989-11-15 | — | — | EP | disclosed |