SCHEMBL118593

SCHEMBL118593

COc1cc(C=Cc2ccccc2)c(OC)c(OC)c1OC

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TUBB1 Q9H4B7 10/20 0.69
TUBB4A P04350 9/20 0.69
TUBB P07437 9/20 0.69
TUBA3C P0DPH7 9/20 0.69
TUBA1B P68363 9/20 0.69
TUBA4A P68366 9/20 0.69
TUBB4B P68371 9/20 0.69
TUBB3 Q13509 9/20 0.69
TUBB2A Q13885 9/20 0.69
TUBB8 Q3ZCM7 9/20 0.69
TUBA3E Q6PEY2 9/20 0.69
TUBA1A Q71U36 9/20 0.69
TUBA1C Q9BQE3 9/20 0.69
TUBB6 Q9BUF5 9/20 0.69
TUBB2B Q9BVA1 9/20 0.69
NFE2L2 Q16236 2/20 0.63
TRPA1 O75762 1/20 0.61
CYP1A1 P04798 4/20 0.57
CYP1B1 Q16678 4/20 0.57
CYP1A2 P05177 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29136491 1.00 TUBB1 (0.69) TUBB1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL29136488 1.00 TUBB1 (0.69) TUBB1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL9243542 0.87 TUBB1 (0.75) TUBB1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL9243558 0.87 TUBB1 (0.75) TUBB1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL17938788 0.85 TUBB1 (0.63) TUBB1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL27835441 0.85 TUBB1 (0.63) TUBB1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL17938785 0.85 TUBB1 (0.63) TUBB1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL27723385 0.85 TUBB1 (0.58) TUBB1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL27835357 0.85 TUBB1 (0.63) TUBB1TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL235883 0.84 NFE2L2 (0.75) TUBB1TUBB4ATUBBTUBA3CTUBA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 240 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117561081-A Application of CYP450 inhibitor in inhibiting or killing mites and treating xerophthalmia 广州珍实视界生物医药科技有限公司 2024-02-13 CN claimed
CN-117222406-A Compounds for the treatment and prophylaxis of covd-19 T·塞凯赖什 2023-12-12 CN claimed
US-20230141224-A1 FIBROBLAST MEDIATED EXPANSION AND AUGMENTATION OF IMMUNE REGULATORY CELLS FOR TREATMENT OF ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) FIGENE, LLC 2023-05-11 US claimed
EP-4142751-A1 FIBROBLAST MEDIATED EXPANSION AND AUGMENTATION OF IMMUNE REGULATORY CELLS FOR TREATMENT OF ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) Figene, LLC (US) 2023-03-08 EP claimed
CN-114796470-A Resveratrol compound and CAR-T cell targeting NKG2D ligand combined preparation of medicine for treating malignant tumor 深圳宾德生物技术有限公司 2022-07-29 CN claimed
WO-2021202032-A1 FIBROBLAST MEDIATED EXPANSION AND AUGMENTATION OF IMMUNE REGULATORY CELLS FOR TREATMENT OF ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) FIGENE, LLC (US) 2021-10-07 WO claimed
WO-2018210880-A1 STILBENES FOR PRE-HARVEST TREATMENT AND CROP PROTECTION EVOLVA SA (CH) 2018-11-22 WO claimed
WO-2018210872-A1 STILBENES FOR POST-HARVEST TREATMENT AND FOOD PRESERVATION AND/OR SHELF LIFE EXTENSION EVOLVA SA (CH) 2018-11-22 WO claimed
US-20160215306-A1 METHOD FOR PRODUCING MODIFIED RESVERATROL EVOLVA SA (CH) 2016-07-28 US claimed
EP-3039132-A2 A METHOD FOR PRODUCING MODIFIED RESVERATROL Evolva SA (CH) 2016-07-06 EP claimed
WO-2009001046-A2 [11C]METHOXY-RADIOLABELLED 2,3',4,5'-TETRAMETHYLSTILBENE (TMS) AND ITS PREPARATION AND USE THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN (GB) 2008-12-31 WO claimed
EP-1450819-A4 METHODS AND COMPOSITIONS FOR PREVENTION AND TREATMENT OF INFLAMMATORY DISEASE, AUTOIMMUNE DISEASE, AND TRANSPLANT REJECTION UNIV CALIFORNIA (US) 2008-01-23 EP claimed
CN-1729007-A Compositions and methods for preventing and treating inflammatory diseases, autoimmune diseases, and transplant rejection UNIV CALIFORNIA (US) 2006-02-01 CN claimed
US-20040242500-A1 Methods and compositions for prevention and treatment of inflammatory disease, autoimmune disease, and transplant rejection THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2004-12-02 US claimed
EP-1450819-A1 METHODS AND COMPOSITIONS FOR PREVENTION AND TREATMENT OF INFLAMMATORY DISEASE, AUTOIMMUNE DISEASE, AND TRANSPLANT REJECTION The Regents of the University of California (US) 2004-09-01 EP claimed
WO-2003039557-A1 METHODS AND COMPOSITIONS FOR PREVENTION AND TREATMENT OF INFLAMMATORY DISEASE, AUTOIMMUNE DISEASE, AND TRANSPLANT REJECTION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2003-05-15 WO claimed
EP-1045853-A4 SYNTHESIS OF COMBRETASTATIN A-4 PRODRUGS AND TRANS-ISOMERS THEREO F UNIV ARIZONA STATE (US) 2002-04-17 EP claimed
JP-2002500227-A 2002-01-08 JP claimed
WO-2001021165-A1 RESVERATROL ANALOGS FOR PREVENTION OF DISEASE RUTGERS, THE STATE UNIVERSITY (US) 2001-03-29 WO claimed
EP-1045853-A1 SYNTHESIS OF COMBRETASTATIN A-4 PRODRUGS AND TRANS-ISOMERS THEREO F ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA acting for and on behalf of ARIZONA STATE UNIVERSITY (US) 2000-10-25 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040242500-A1 Methods and compositions for prevention and treatment of inflammatory disease, autoimmune disease, and transplant rejection TNF, HLA-DRB1, IL5 TUBB1 1374/4885TUBB4A 1463/4885TUBB 1649/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.