Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10523982 | 1.00 | LMNA (0.47) | LMNACYP2A6CHRNA7RAB9AFTO | |
| SCHEMBL4388070 | 0.92 | TSHR (0.48) | LMNACYP2A6CHRNA7RAB9AKDM4E | |
| SCHEMBL4388071 | 0.92 | TSHR (0.48) | LMNACYP2A6CHRNA7RAB9AKDM4E | |
| SCHEMBL11287657 | 0.88 | MDM2 (0.48) | LMNACYP2A6CHRNA7RAB9AFTO | |
| SCHEMBL14155985 | 0.82 | SLC6A2 (0.44) | RAB9AL3MBTL1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4385331 | 0.82 | SLC6A2 (0.44) | RAB9AL3MBTL1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18527323 | 0.81 | CHRNA7 (0.48) | LMNACYP2A6CHRNA7RAB9AFTO | |
| SCHEMBL18538074 | 0.81 | CHRNA7 (0.48) | LMNACYP2A6CHRNA7RAB9AFTO | |
| SCHEMBL16034206 | 0.81 | CHRNA7 (0.48) | LMNACYP2A6CHRNA7RAB9AFTO | |
| SCHEMBL18527321 | 0.81 | CHRNA7 (0.48) | LMNACYP2A6CHRNA7RAB9AFTO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171753-A | Derivatives of 2-amino-1-phenylethanol having antiulcer activity | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-12-15 | — | — | US | disclosed |
| US-4803200-A | SHIPPING FEVER SYNDROME | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-02-07 | — | — | US | disclosed |
| US-4013723-A | REACTION OF AN OXIRANE WITH HYDROGEN PEROXIDE | BAYER AKTIENGESELLSCHAFT (DT) | 1977-03-22 | — | — | US | disclosed |
| US-3974224-A | HYDROGEN PEROXIDE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-10 | — | — | US | disclosed |