SCHEMBL4385331

SCHEMBL4385331

Clc1ccc(C2OC2c2ccccc2Cl)cc1

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 3/20 0.44
SLC6A3 Q01959 2/20 0.44
PRCP P42785 1/20 0.39
RAB9A P51151 1/20 0.37
HTR2A P28223 1/20 0.37
HTR2C P28335 1/20 0.37
HTR2B P41595 1/20 0.37
GAA P10253 1/20 0.37
KMT2A Q03164 1/20 0.37
SLC6A4 P31645 1/20 0.36
L3MBTL4 Q8NA19 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14155985 1.00 SLC6A2 (0.44) SLC6A2SLC6A3PRCPRAB9AHTR2A
SCHEMBL93210 0.88 SLC6A3 (0.41) SLC6A3HTR2AHTR2CHTR2BGAA
SCHEMBL11201145 0.85 TSHR (0.47) HTR2AHTR2CHTR2BGAAKMT2A
SCHEMBL30064748 0.85 EPHX1 (0.40) PRCPHTR2AHTR2CHTR2BKMT2A
SCHEMBL9729085 0.82 LMNA (0.47) SLC6A2SLC6A3RAB9AKMT2ASLC6A4
SCHEMBL10523982 0.82 LMNA (0.47) SLC6A2SLC6A3RAB9AKMT2ASLC6A4
SCHEMBL4388070 0.81 TSHR (0.48) SLC6A3RAB9AKMT2AL3MBTL1
SCHEMBL4388071 0.81 TSHR (0.48) SLC6A3RAB9AKMT2AL3MBTL1
SCHEMBL8535573 0.77 ALDH1A1 (0.43) HTR2AHTR2CHTR2B
SCHEMBL7459225 0.77 ALDH1A1 (0.43) HTR2AHTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7629400-B2 Image making medium HYMAN SYDNEY 2009-12-08 US disclosed
US-20030035917-A1 Image making medium HYMAN SYDNEY (US) 2003-02-20 US disclosed