Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | PPID | Q08752 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1770251 | 0.85 | CPB1 (0.52) | CCR1ALDH1A1CYP2C9CYP2C19GAA | |
| SCHEMBL12987132 | 0.84 | PPID (0.41) | PPIDMEN1KMT2AMAPTPKM | |
| SCHEMBL12987139 | 0.84 | PPID (0.41) | PPIDMEN1KMT2AMAPTPKM | |
| SCHEMBL12987135 | 0.84 | PPID (0.41) | PPIDMEN1KMT2AMAPTPKM | |
| SCHEMBL13137383 | 0.83 | CCR1 (0.54) | CCR1MAPTPKMSMN1; SMN2KDM4E | |
| SCHEMBL2993771 | 0.81 | ALDH1A1 (0.41) | CCR1ALDH1A1MAPTPKMSMN1; SMN2 | |
| SCHEMBL3680990 | 0.81 | ALDH1A1 (0.41) | CCR1ALDH1A1MAPTPKMSMN1; SMN2 | |
| SCHEMBL3745167 | 0.81 | ALDH1A1 (0.41) | CCR1ALDH1A1MAPTPKMSMN1; SMN2 | |
| SCHEMBL4460390 | 0.81 | ALDH1A1 (0.41) | CCR1ALDH1A1MAPTPKMSMN1; SMN2 | |
| SCHEMBL4485950 | 0.81 | ALDH1A1 (0.41) | CCR1ALDH1A1MAPTPKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134143-A | Dopamine Agonists | ELI LILLY AND COMPANY (US) | 1992-07-28 | — | — | US | disclosed |
| US-4977160-A | DOPAMINE AGONISTS; PARKINSON*S DISEASE | ELI LILLY AND COMPANY (US) | 1990-12-11 | — | — | US | disclosed |
| US-4826986-A | DOPAMINE AGONISTS | ELI LILLY AND COMPANY (US) | 1989-05-02 | — | — | US | disclosed |
| EP-0250179-A2 | BCD tricyclic ergoline part-structure analogues | ELI LILLY AND COMPANY (US) | 1987-12-23 | — | — | EP | disclosed |