SCHEMBL9729146

SCHEMBL9729146

OCCC(CO)CNC(c1ccccc1)C(O)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 5/20 0.46
MAN2A1 Q16706 2/20 0.41
MAN1B1 Q9UKM7 2/20 0.41
SLC6A2 P23975 4/20 0.37
SLC6A4 P31645 4/20 0.37
SLC6A3 Q01959 4/20 0.37
CYP3A4 P08684 3/20 0.37
CYP2D6 P10635 3/20 0.37
KCNH2 Q12809 1/20 0.37
KDM4E B2RXH2 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
TRPA1 O75762 2/20 0.36
ALDH1A1 P00352 1/20 0.35
CHRM2 P08172 1/20 0.35
ADRA1A P35348 1/20 0.35
RGS12 O14924 1/20 0.35
GLA P06280 1/20 0.35
CYP2C9 P11712 1/20 0.35
PKM P14618 1/20 0.35
ALOX15 P16050 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9728971 0.80 AOC3 (0.52) AOC3MAN2A1MAN1B1SLC6A2SLC6A4
SCHEMBL9729326 0.78 AOC3 (0.57) AOC3MAN2A1MAN1B1SLC6A2SLC6A4
SCHEMBL9729227 0.76 AOC3 (0.55) AOC3MAN2A1MAN1B1SLC6A2SLC6A4
SCHEMBL9729467 0.75 AOC3 (0.53) AOC3MAN2A1MAN1B1SLC6A2SLC6A4
SCHEMBL29433956 0.75 AOC3 (0.53) AOC3MAN2A1MAN1B1SLC6A2SLC6A4
SCHEMBL9728901 0.73 ALDH1A1 (0.54) AOC3MAN2A1MAN1B1SLC6A2SLC6A4
SCHEMBL9729228 0.72 AOC3 (0.50) AOC3MAN2A1MAN1B1SLC6A2SLC6A4
SCHEMBL10523671 0.71 AOC3 (0.49) AOC3MAN2A1MAN1B1CYP3A4CYP2D6
SCHEMBL9729722 0.71 AOC3 (0.49) AOC3MAN2A1MAN1B1SLC6A2SLC6A4
SCHEMBL9729174 0.71 AOC3 (0.49) AOC3MAN2A1MAN1B1CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5171753-A Derivatives of 2-amino-1-phenylethanol having antiulcer activity A. H. ROBINS COMPANY, INCORPORATED (US) 1992-12-15 US disclosed