SCHEMBL240366

SCHEMBL240366

CCCCN(CC#N)CCCC

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.43
CYP1A2 P05177 2/20 0.42
MAPK1 P28482 1/20 0.42
ZDHHC20 Q5W0Z9 3/20 0.39
ZDHHC2 Q9UIJ5 1/20 0.39
KCNH2 Q12809 4/20 0.35
CA12 O43570 2/20 0.34
CA1 P00915 2/20 0.34
CA9 Q16790 2/20 0.34
MAPT P10636 1/20 0.33
LCK P06239 1/20 0.33
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19497014 0.97 TSHR (0.42) TSHRCYP1A2MAPK1ZDHHC20ZDHHC2
SCHEMBL19999960 0.95 TSHR (0.43) TSHRCYP1A2MAPK1ZDHHC20ZDHHC2
SCHEMBL5081835 0.90 ZDHHC20 (0.49) TSHRCYP1A2MAPK1ZDHHC20ZDHHC2
SCHEMBL4170086 0.90 ZDHHC20 (0.49) TSHRCYP1A2MAPK1ZDHHC20ZDHHC2
SCHEMBL21467473 0.90 KCNH2 (0.44) TSHRCYP1A2MAPK1ZDHHC20ZDHHC2
SCHEMBL11023925 0.87 ZDHHC20 (0.46) TSHRCYP1A2MAPK1ZDHHC20ZDHHC2
SCHEMBL4173370 0.86 CYP1A2 (0.48) TSHRCYP1A2MAPK1ZDHHC20ZDHHC2
SCHEMBL20756343 0.85 CYP1A2 (0.52) TSHRCYP1A2MAPK1ZDHHC20ZDHHC2
SCHEMBL10646289 0.81 KCNH2 (0.47) ZDHHC20ZDHHC2KCNH2
SCHEMBL20369039 0.80 CYP1A2 (0.48) TSHRCYP1A2MAPK1ZDHHC20ZDHHC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090023942-A1 Method for Producing Bi-Functional Ammonium Nitriles CLARIANT PRODUKTE (DEUTSCHALND) GMBH (DE) 2009-01-22 US claimed
EP-1856034-A1 METHOD FOR PRODUCING BIFUNCTIONAL AMMONIUM NITRILES Clariant Produkte (Deutschland) GmbH (DE) 2007-11-21 EP claimed
WO-2006092247-A1 METHOD FOR PRODUCING BIFUNCTIONAL AMMONIUM NITRILES CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2006-09-08 WO claimed
US-4737568-A Curable resin from bis-imide amino acid hydrazide and alkenyl phenol or ether THE BOOTS COMPANY PLC (GB) 1988-04-12 US claimed
EP-0212808-A2 Curable resins Technochemie GmbH - Verfahrenstechnik (DE) 1987-03-04 EP claimed
US-4404167-A AMINO NITRILE INHIBITORS ROZENFELD IOSIF L 1983-09-13 US claimed
US-9512333-B2 Phosphoric acid resistant polymaleimide prepolymer compositions HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2016-12-06 US disclosed
EP-2417168-B1 PHOSPHORIC ACID RESISTANT POLYMALEIMIDE PREPOLYMER COMPOSITIONS HUNTSMAN ADV MAT AMERICAS INC (US) 2014-11-26 EP disclosed
EP-2710045-A1 HALOGEN FREE THERMOSET RESIN SYSTEM FOR LOW DIELECTRIC LOSS AT HIGH FREQUENCY APPLICATIONS Huntsman Advanced Materials Americas LLC (US) 2014-03-26 EP disclosed
US-20140057086-A1 Halogen Free Thermoset Resin System for Low Dielectric Loss at High Frequency Applications HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2014-02-27 US disclosed
US-20130231021-A1 Phosphoric Acid Resistant Polymaleimide Prepolymer Compositions HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2013-09-05 US disclosed
US-8445699-B2 Phosphoric acid resistant polymaleimide prepolymer compositions HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2013-05-21 US disclosed
WO-2012158415-A1 HALOGEN FREE THERMOSET RESIN SYSTEM FOR LOW DIELECTRIC LOSS AT HIGH FREQUENCY APPLICATIONS HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2012-11-22 WO disclosed
US-4131707-A POLYMALEIMIDES CIBA-GEIGY CORPORATION (US) 1978-12-26 US disclosed
US-4100140-A REACTING POLYMALEIMIDES WITH ALKENYLPHENOLS OR ALKENYLPHENOL ETHERS, POLYMERIZATION CATALYSTS CIBA-GEIGY CORPORATION (US) 1978-07-11 US disclosed
US-4076697-A FROM POLYIMIDES AND POLYCARBOXYLIC ACIDS IN THE PRESENCE OF AN AMINE CIBA-GEIGY CORPORATION (US) 1978-02-28 US disclosed
US-4066621-A CURABLE MIXTURES BASED ON POLYIMIDES OF UNSATURATED DICARBOXYLIC ACIDS AND INDOLE COMPOUNDS CIBA-GEIGY CORPORATION (US) 1978-01-03 US disclosed
US-4065433-A Process for the manufacture of polyaddition products containing imide groups CIBA-GEIGY CORPORATION (US) 1977-12-27 US disclosed
US-4046777-A INTERMEDIATES FOR HEAT-RESISTANT POLYMERS CIBA-GEIGY CORPORATION (US) 1977-09-06 US disclosed
US-4038251-A PROCESS FOR THE MANUFACTURE OF POLYADDITION PRODUCTS CONTAINING IMIDE GROUPS BY REACTION OF POLYMALEIMIDES WITH POLYHYDRIC PHENOLS USING AMINE CATALYST CIBA-GEIGY CORPORATION (US) 1977-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090023942-A1 Method for Producing Bi-Functional Ammonium Nitriles DBF4, AADAC, NAAA TSHR 4024/4885CYP1A2 194/4885MAPK1 2786/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.