Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | TACR1 | P25103 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9730595 | 0.85 | TACR1 (0.58) | MEN1KMT2AMAPTTACR1TSHR | |
| SCHEMBL9729849 | 0.85 | TACR1 (0.58) | MEN1KMT2AMAPTTACR1TSHR | |
| SCHEMBL9729926 | 0.84 | TACR1 (0.55) | MEN1KMT2AMAPTTACR1TSHR | |
| SCHEMBL9731812 | 0.82 | TACR1 (0.48) | MEN1KMT2AMAPTTACR1TSHR | |
| SCHEMBL9729330 | 0.82 | TACR1 (0.52) | MEN1KMT2AMAPTTACR1TSHR | |
| SCHEMBL9729456 | 0.81 | TACR1 (0.59) | MEN1KMT2AMAPTTACR1TSHR | |
| SCHEMBL9730130 | 0.80 | KMT2A (0.53) | MEN1KMT2AMAPTTACR1TSHR | |
| SCHEMBL9729686 | 0.80 | TACR1 (0.58) | MEN1KMT2AMAPTTACR1TSHR | |
| SCHEMBL9730227 | 0.80 | TACR1 (0.53) | MEN1KMT2AMAPTTACR1TSHR | |
| SCHEMBL9730246 | 0.80 | TACR1 (0.58) | MEN1KMT2AMAPTTACR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102667-A | Antiallergens, antiinflammatory agents, nervous system disorders, immunology, psychological disorders | RHONE-POULENC SANTE (FR) | 1992-04-07 | — | — | US | disclosed |